Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YWHAG | P61981 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | PAM | P19021 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17625658 | 0.81 | KMT2A (0.49) | ALDH1A1L3MBTL1PAM | |
| SCHEMBL17600534 | 0.81 | YWHAG (0.44) | YWHAGALOX5PPARGPPARACYP4F2 | |
| SCHEMBL28889136 | 0.80 | YWHAG (0.43) | YWHAGALOX5PPARGPPARACYP4F2 | |
| SCHEMBL17625646 | 0.79 | CA1 (0.31) | CA1CA2 | |
| SCHEMBL17625650 | 0.79 | CES1 (0.35) | L3MBTL1TDP1CA2 | |
| SCHEMBL17484415 | 0.77 | CA2 (0.46) | ALDH1A1GAATSHRTDP1CA2 | |
| SCHEMBL17625647 | 0.75 | ESR1 (0.40) | ALDH1A1GAATSHRMAPK1TDP1 | |
| SCHEMBL16385087 | 0.75 | KMT2A (0.34) | MAPK1 | |
| SCHEMBL19399246 | 0.75 | YWHAG (0.39) | YWHAGALOX5PPARGPPARACYP4F2 | |
| SCHEMBL24862423 | 0.74 | YWHAG (0.39) | YWHAGALOX5PPARGPPARAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10693072-B2 | Diazirine containing organic electronic compositions and device thereof | PROMERUS, LLC (US) | 2020-06-23 | — | — | US | disclosed |
| US-10303060-B2 | Diazirine compounds and compositions derived therefrom | PROMERUS, LLC (US) | 2019-05-28 | — | — | US | disclosed |
| US-20190157558-A1 | DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF | PROMERUS, LLC (US) | 2019-05-23 | — | — | US | disclosed |
| US-10256409-B2 | Diazirine containing organic electronic compositions and device thereof | PROMERUS, LLC (US) | 2019-04-09 | — | — | US | disclosed |
| US-20180186747-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | PROMERUS, LLC (US) | 2018-07-05 | — | — | US | disclosed |
| US-9938241-B2 | Diazirine compounds and compositions derived therefrom | PROMERUS, LLC (US) | 2018-04-10 | — | — | US | disclosed |
| US-20170279048-A1 | DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF | PROMERUS, LLC (US) | 2017-09-28 | — | — | US | disclosed |
| US-20160083352-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | SUMITOMO BAKELITE CO., LTD. (JP) | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083352-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | RDX, AOX1, ALDH1A2 | YWHAG 1741/4885ALOX5 28/4885PPARG 191/4885 |
| US-20180186747-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | ZYX, AOX1, RDX | YWHAG 1933/4885ALOX5 37/4885PPARG 1246/4885 |
| US-10303060-B2 | Diazirine compounds and compositions derived therefrom | ZYX, AOX1, RDX | YWHAG 1933/4885ALOX5 37/4885PPARG 1246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.