Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.80 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.80 |
| ▸ | TP53 | P04637 | 1/20 | 0.80 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.80 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.75 |
| ▸ | ELANE | P08246 | 5/20 | 0.73 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.73 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.67 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.66 |
| ▸ | ESR1 | P03372 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | BCHE | P06276 | 1/20 | 0.64 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.64 |
| ▸ | IDO1 | P14902 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17626653 | 1.00 | ACHE (0.80) | ACHEPTGS2TP53MDM2PDE4D | |
| Cudraflavanone B SCHEMBL23140484 | 0.92 | CACNA1H (0.79) | ACHEPTGS2TP53MDM2PDE4D | |
| Nymphaeol C SCHEMBL16105580 | 0.89 | ELANE (0.76) | ACHEPTGS2TP53MDM2PDE4D | |
| SCHEMBL13682902 | 0.89 | ELANE (0.76) | ACHEPTGS2TP53MDM2PDE4D | |
| Nymphaeol C SCHEMBL16105581 | 0.89 | ELANE (0.76) | ACHEPTGS2TP53MDM2PDE4D | |
| Nymphaeol C SCHEMBL910203 | 0.89 | ELANE (0.76) | ACHEPTGS2TP53MDM2PDE4D | |
| Nymphaeol C SCHEMBL7796382 | 0.89 | ELANE (0.76) | ACHEPTGS2TP53MDM2PDE4D | |
| Nymphaeol C SCHEMBL29375168 | 0.89 | ELANE (0.76) | ACHEPTGS2TP53MDM2PDE4D | |
| Bonannione A SCHEMBL16105830 | 0.89 | ACHE (1.00) | ACHEPTGS2TP53MDM2PDE4D | |
| Bonannione A SCHEMBL140804 | 0.89 | ACHE (1.00) | ACHEPTGS2TP53MDM2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10633358-B2 | T-type calcium channel inhibitor | KINKI UNIVERSITY (JP) | 2020-04-28 | — | — | US | disclosed |
| US-20180065947-A1 | T-TYPE CALCIUM CHANNEL INHIBITOR | UNIV KINKI (JP) | 2018-03-08 | — | — | US | disclosed |
| US-20160096815-A1 | T-TYPE CALCIUM CHANNEL INHIBITOR | KINKI UNIVERSITY (JP) | 2016-04-07 | — | — | US | disclosed |
| EP-3000465-A1 | T-TYPE CALCIUM CHANNEL INHIBITOR | Kinki University (JP) | 2016-03-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160096815-A1 | T-TYPE CALCIUM CHANNEL INHIBITOR | CACNA1G, CACNA1H, CACNA1I | ACHE 1618/4885PTGS2 1567/4885TP53 3382/4885 |
| US-20180065947-A1 | T-TYPE CALCIUM CHANNEL INHIBITOR | CACNA1G, CACNA1H, CACNA1I | ACHE 1582/4885PTGS2 1520/4885TP53 3340/4885 |
| US-10633358-B2 | T-type calcium channel inhibitor | CACNA1G, CACNA1H, CACNA1I | ACHE 1582/4885PTGS2 1520/4885TP53 3340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.