Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 1.00 |
| ▸ | PTGS2 | P35354 | 4/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | MDM2 | Q00987 | 1/20 | 1.00 |
| ▸ | ELANE | P08246 | 6/20 | 0.84 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.84 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.83 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.83 |
| ▸ | ESR1 | P03372 | 1/20 | 0.83 |
| ▸ | MAPT | P10636 | 1/20 | 0.83 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.83 |
| ▸ | ATM | Q13315 | 1/20 | 0.83 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.83 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.76 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.66 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.66 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.66 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bonannione A SCHEMBL16105830 | 1.00 | ACHE (1.00) | ACHEPTGS2TP53MDM2ELANE | |
| Bonannione A SCHEMBL3231728 | 1.00 | ACHE (1.00) | ACHEPTGS2TP53MDM2ELANE | |
| Bonannione A SCHEMBL29904527 | 1.00 | ACHE (1.00) | ACHEPTGS2TP53MDM2ELANE | |
| Bonannione A SCHEMBL12780391 | 1.00 | ACHE (1.00) | ACHEPTGS2TP53MDM2ELANE | |
| SCHEMBL18061372 | 0.94 | ACHE (0.88) | ACHEPTGS2TP53MDM2ELANE | |
| SCHEMBL7794615 | 0.94 | ACHE (0.88) | ACHEPTGS2TP53MDM2ELANE | |
| SCHEMBL4254357 | 0.93 | ACHE (0.86) | ACHEPTGS2TP53MDM2ELANE | |
| Nymphaeol A SCHEMBL7795014 | 0.92 | ELANE (1.00) | ACHEPTGS2TP53MDM2ELANE | |
| Nymphaeol A SCHEMBL16105856 | 0.92 | ELANE (1.00) | ACHEPTGS2TP53MDM2ELANE | |
| Nymphaeol A SCHEMBL909992 | 0.92 | ELANE (1.00) | ACHEPTGS2TP53MDM2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051551-A1 | IMPROVED POLYMER COMPOSITES | WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) | 2025-02-13 | — | — | US | claimed |
| WO-2023193244-A1 | SUPRAMOLECULAR SELF-ASSEMBLY SYSTEM | 北京睿创康泰医药研究院有限公司 | 2023-10-12 | — | — | WO | claimed |
| EP-4216920-A1 | ORAL CARE COMPOSITIONS COMPRISING PRENYLATED FLAVONOIDS | The Procter & Gamble Company (US) | 2023-08-02 | — | — | EP | claimed |
| WO-2022067143-A1 | ORAL CARE COMPOSITIONS COMPRISING PRENYLATED FLAVONOIDS | THE PROCTER & GAMBLE COMPANY (US) | 2022-03-31 | — | — | WO | claimed |
| US-20220096364-A1 | Oral Care Compositions Comprising Prenylated Flavonoid | THE PROCTER & GAMBLE COMPANY | 2022-03-31 | — | — | US | claimed |
| US-20190046469-A1 | COMPOSITIONS AND METHODS FOR TREATING MOOD DISORDERS OR SKIN DISEASE OR DAMAGE | KUHRTS ERIC HAUSER (US) | 2019-02-14 | — | — | US | claimed |
| US-20150209307-A1 | COMPOSITIONS AND METHODS FOR TREATING MOOD DISORDERS OR SKIN DISEASE OR DAMAGE | KUHRTS ERIC HAUSER (US) | 2015-07-30 | — | — | US | claimed |
| WO-2014025989-A1 | COMPOSITIONS AND METHODS FOR TREATING MOOD DISORDERS OR SKIN DISEASE OR DAMAGE | KUHRTS ERIC HAUSER (US) | 2014-02-13 | — | — | WO | claimed |
| US-20140045904-A1 | NIACIN FORMULATIONS AND METHODS WITH REDUCED FLUSHING SIDE EFFECT | KUHRTS ERIC HAUSER (US) | 2014-02-13 | — | — | US | claimed |
| WO-2012051107-A2 | NIACIN FORMULATIONS AND METHODS WITH REDUCED FLUSHING SIDE-EFFECT | KUHRTS ERIC HAUSER (US) | 2012-04-19 | — | — | WO | claimed |
| US-20090209654-A1 | Prenylflavonoid Formulations | BIOACTIVES, INC. | 2009-08-20 | — | — | US | claimed |
| WO-2008095189-A1 | METHODS AND COMPOSITIONS FOR TREATING DYSLIPIDAEMIA | BIOACTIVES, INC. (US) | 2008-08-07 | — | — | WO | claimed |
| WO-2008089137-A1 | HOPS EXTRACTION METHODS AND MIXTURES | BIOACTIVES, INC. (US) | 2008-07-24 | — | — | WO | claimed |
| EP-1909584-A2 | PRENYLFLAVONOID FORMULATIONS | Bioactives, Inc. (US) | 2008-04-16 | — | — | EP | claimed |
| US-20070218155-A1 | Methods and compositions for treating dyslipidaemia | BIOACTIVES, INC. | 2007-09-20 | — | — | US | claimed |
| WO-2007016578-A2 | PRENYLFLAVONOID FORMULATIONS | BIOACTIVES, INC. (US) | 2007-02-08 | — | — | WO | claimed |
| US-20050019438-A1 | Hop extracts and use thereof in the production of a medicament having estrogenic properties | BOURGES-SEVENIER CEDRIC (FR) | 2005-01-27 | — | — | US | claimed |
| EP-1381379-A1 | HOP EXTRACTS AND USE THEREOF IN THE PRODUCTION OF A MEDICAMENT HAVING ESTROGENIC PROPERTIES | BERKEM (FR) | 2004-01-21 | — | — | EP | claimed |
| WO-2002085393-A1 | HOP EXTRACTS AND USE THEREOF IN THE PRODUCTION OF A MEDICAMENT HAVING ESTROGENIC PROPERTIES | BERKEM (FR) | 2002-10-31 | — | — | WO | claimed |
| WO-2001003687-A2 | METHOD AND COMPOSITIONS FOR INHIBITING BIOSYNTHESIS OR BIOACTIVITY OF ENDOGENOUS STEROID SEX HORMONES IN HUMANS | CEDARS-SINAI MEDICAL CENTER (US) | 2001-01-18 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150209307-A1 | COMPOSITIONS AND METHODS FOR TREATING MOOD DISORDERS OR SKIN DISEASE OR DAMAGE | CUTA, PSEN2, PNN | ACHE 808/4885PTGS2 2094/4885TP53 1146/4885 |
| US-20190046469-A1 | COMPOSITIONS AND METHODS FOR TREATING MOOD DISORDERS OR SKIN DISEASE OR DAMAGE | CUTA, PSEN2, PNN | ACHE 808/4885PTGS2 2094/4885TP53 1146/4885 |
| US-20220096364-A1 | Oral Care Compositions Comprising Prenylated Flavonoid | PROC, F9, SP1 | ACHE 309/4885PTGS2 4259/4885TP53 2293/4885 |
| US-20140045904-A1 | NIACIN FORMULATIONS AND METHODS WITH REDUCED FLUSHING SIDE EFFECT | NAPRT, NISCH, NAMPT | ACHE 1104/4885PTGS2 1870/4885TP53 4333/4885 |
| US-20090209654-A1 | Prenylflavonoid Formulations | TP53, CYP46A1, HPGD | ACHE 4372/4885PTGS2 311/4885TP53 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.