Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18591511 | 0.87 | HPGD (0.55) | ALDH1A1HPGDNPC1RAB9ATP53 | |
| SCHEMBL26659429 | 0.83 | BRD4 (0.46) | ALDH1A1HPGDNPC1RAB9ATP53 | |
| SCHEMBL28972277 | 0.80 | KDM4E (0.63) | ALDH1A1HPGDNPC1RAB9ATP53 | |
| SCHEMBL17627049 | 0.80 | P2RX7 (0.47) | ALDH1A1TP53KDM4EMAPTGAA | |
| SCHEMBL25415963 | 0.77 | FAAH (0.53) | ALDH1A1HPGDNPC1RAB9ATP53 | |
| SCHEMBL16827651 | 0.77 | HPGD (0.56) | ALDH1A1HPGDNPC1RAB9ATP53 | |
| SCHEMBL5803621 | 0.77 | NPC1 (0.52) | ALDH1A1HPGDNPC1RAB9ATP53 | |
| SCHEMBL18611566 | 0.77 | NPSR1 (0.46) | ALDH1A1MAPTGAANPSR1LMNA | |
| SCHEMBL4700631 | 0.75 | HPGD (0.67) | ALDH1A1HPGDNPC1RAB9ATP53 | |
| SCHEMBL1077879 | 0.75 | HPGD (0.50) | ALDH1A1HPGDNPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2999338-B1 | KNOWN AND NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2017-07-12 | — | — | EP | disclosed |
| US-20160106102-A1 | KNOWN AND NEW HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-04-21 | — | — | US | disclosed |
| EP-2999338-A1 | KNOWN AND NEW HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2016-03-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160106102-A1 | KNOWN AND NEW HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | DDT, ACHE, NISCH | ALDH1A1 2634/4885HPGD 627/4885NPC1 3893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.