Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17630007 | 0.96 | HRH2 (0.36) | HRH2HRH1TSHRHSD17B10HPGD | |
| SCHEMBL17629919 | 0.80 | KDM1A (0.37) | KDM1ACYP11B1CYP11B2 | |
| SCHEMBL17629889 | 0.77 | TSHR (0.34) | TSHRHSD17B10HPGDALDH1A1KDM4E | |
| SCHEMBL17629868 | 0.77 | TLR7 (0.34) | TSHRHSD17B10HPGDALDH1A1KDM4E | |
| SCHEMBL17629950 | 0.75 | PDE2A (0.48) | TSHRHSD17B10CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL17672927 | 0.73 | SLC6A4 (0.33) | TSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL4314504 | 0.72 | TSHR (0.44) | TSHRHSD17B10ALDH1A1KDM1ACYP11B2 | |
| SCHEMBL17629925 | 0.72 | SLC6A4 (0.34) | TSHRHSD17B10RAB9ASMN1; SMN2 | |
| SCHEMBL4455682 | 0.72 | TSHR (0.48) | TSHRHSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL17630083 | 0.72 | CYP2D6 (0.42) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016046782-A1 | IMIDAZOLE BIARYL COMPOUNDS AS S-NITROSOGLUTATHIONE REDUCTASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2016-03-31 | — | — | WO | disclosed |