SCHEMBL4314504

SCHEMBL4314504

CCCCc1cc(C#N)ccc1-c1ccc(C)cc1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ALDH1A1 P00352 1/20 0.43
CYP2A6 P11509 1/20 0.43
KDM1A O60341 13/20 0.41
CYP11B2 P19099 1/20 0.38
DRD2 P14416 1/20 0.37
DRD3 P35462 1/20 0.37
FNTA P49354 1/20 0.36
FNTB P49356 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28273598 0.87 ADRA2C (0.44) TSHRHSD17B10ALDH1A1CYP11B2DRD2
SCHEMBL4455682 0.82 TSHR (0.48) TSHRHSD17B10ALDH1A1CYP11B2DRD2
SCHEMBL9211839 0.81 TSHR (0.50) TSHRHSD17B10ALDH1A1CYP11B2
SCHEMBL10340506 0.81 TSHR (0.50) TSHRHSD17B10ALDH1A1CYP11B2
SCHEMBL10340558 0.81 TSHR (0.50) TSHRHSD17B10ALDH1A1CYP11B2
SCHEMBL5697352 0.81 TSHR (0.50) TSHRHSD17B10ALDH1A1CYP11B2
SCHEMBL5307030 0.81 TSHR (0.50) TSHRHSD17B10ALDH1A1CYP11B2
SCHEMBL10875688 0.77 KDM1A (0.49) TSHRHSD17B10ALDH1A1CYP2A6KDM1A
SCHEMBL11994130 0.77 TSHR (0.51) TSHRHSD17B10ALDH1A1CYP2A6CYP11B2
SCHEMBL30477373 0.77 ADRA2C (0.47) ALDH1A1CYP11B2FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103154807-B There is double glazing goods and the manufacture method thereof of the variable scattering that liquid crystal realizes SAINT-GOBAIN GLASS FRANCE (FR) 2016-01-20 CN disclosed
CN-103154807-A Multiple glazing with variable diffusion by liquid crystals and production method thereof SAINT GOBAIN 2013-06-12 CN disclosed
EP-2128688-A1 Electrically switchable privacy glass pane Saint-Gobain Glass France S.A. (FR) 2009-12-02 EP disclosed
EP-1488277-A4 SWITCHABLE ELECTRO-OPTICAL LAMINATES AVERY DENNISON CORP (US) 2006-08-16 EP disclosed
US-7023600-B2 Switchable electro-optical laminates AVERY DENNISON CORPORATION (US) 2006-04-04 US disclosed
US-20050083564-A1 Switchable electro-optical laminates MALLYA PRAKASH (US) 2005-04-21 US disclosed
EP-1488277-A2 SWITCHABLE ELECTRO-OPTICAL LAMINATES AVERY DENNISON CORPORATION (US) 2004-12-22 EP disclosed
US-20030193709-A1 Switchable electro-optical laminates AVERY DENNISON CORPORATION 2003-10-16 US disclosed
WO-2003083523-A2 SWITCHABLE ELECTRO-OPTICAL LAMINATES AVERY DENNISON CORPORATION (US) 2003-10-09 WO disclosed
EP-0641372-B1 LIQUID CRYSTALLINE LIGHT MODULATING DEVICE & MATERIAL UNIV KENT STATE OHIO (US) 1999-04-21 EP disclosed
US-5437811-A Liquid crystalline light modulating device and material KENT STATE UNIVERSITY (US) 1995-08-01 US disclosed
EP-0641372-A1 LIQUID CRYSTALLINE LIGHT MODULATING DEVICE & MATERIAL KENT STATE UNIVERSITY (US) 1995-03-08 EP disclosed
US-5384067-A Grey scale liquid crystal material KENT STATE UNIVERSITY (US) 1995-01-24 US disclosed
EP-0582656-A4 1994-04-13 EP disclosed
EP-0582656-A1 CRYSTALLINE LIGHT MODULATING DEVICE AND MATERIAL KENT STATE UNIVERSITY (US) 1994-02-16 EP disclosed
WO-1993023496-A1 LIQUID CRYSTALLINE LIGHT MODULATING DEVICE & MATERIAL KENT STATE UNIVERSITY (US) 1993-11-25 WO disclosed
US-5172256-A Liquid crystal variable color density lens and eye protective devices incorporating the same LIQUID CRYSTAL OPTICS INSTITUTE, INC. 1992-12-15 US disclosed
WO-1992019695-A2 CRYSTALLINE LIGHT MODULATING DEVICE AND MATERIAL KENT STATE UNIVERSITY (US) 1992-11-12 WO disclosed
US-4624532-A IMPROVED COLOR FOR ELECTRO-OPTICAL DISPLAYS GENERAL ELECTRIC COMPANY (US) 1986-11-25 US disclosed
US-4356102-A Dichroic liquid crystal compositions containing anthraquinone-based dyes GENERAL ELECTRIC COMPANY (US) 1982-10-26 US disclosed