SCHEMBL176310

SCHEMBL176310

CCCCCCCCCCCC(=O)N1CCCCCC1=O

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.59
L3MBTL1 Q9Y468 2/20 0.56
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
NAAA Q02083 3/20 0.55
FAAH O00519 1/20 0.55
GAA P10253 1/20 0.45
GNAI3 P08754 4/20 0.43
GNAI1 P63096 4/20 0.43
GNAO1 P09471 3/20 0.41
POLB P06746 1/20 0.41
MITF O75030 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ALOX5 P09917 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9576425 1.00 LMNA (0.59) LMNAL3MBTL1MEN1KMT2ATDP1
SCHEMBL8382827 1.00 LMNA (0.59) LMNAL3MBTL1MEN1KMT2ATDP1
SCHEMBL8381990 1.00 LMNA (0.59) LMNAL3MBTL1MEN1KMT2ATDP1
SCHEMBL8378626 1.00 LMNA (0.59) LMNAL3MBTL1MEN1KMT2ATDP1
SCHEMBL4329889 1.00 LMNA (0.59) LMNAL3MBTL1MEN1KMT2ATDP1
SCHEMBL9576378 1.00 LMNA (0.59) LMNAL3MBTL1MEN1KMT2ATDP1
SCHEMBL4141304 1.00 LMNA (0.59) LMNAL3MBTL1MEN1KMT2ATDP1
SCHEMBL9576392 1.00 LMNA (0.59) LMNAL3MBTL1MEN1KMT2ATDP1
SCHEMBL8377436 1.00 LMNA (0.59) LMNAL3MBTL1MEN1KMT2ATDP1
SCHEMBL6659196 1.00 LMNA (0.59) LMNAL3MBTL1MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0268218-B1 PENETRATION ENHANCERS FOR TRANSDERMAL DELIVERY OF SYSTEMIC AGENTS WHITBY RESEARCH, Inc. (US) 1992-05-06 EP claimed
US-4886783-A Penetration enhancers for transdermal delivery of systemic agents NELSON RESEARCH & DEVELOPMENT CO. (US) 1989-12-12 US claimed
EP-0268218-A2 Penetration enhancers for transdermal delivery of systemic agents WHITBY RESEARCH, Inc. (US) 1988-05-25 EP claimed
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES Ananda Scientific, Inc. (US) 2025-06-19 US disclosed
US-12042507-B2 Compositions and methods of modulating HIF-2A to improve muscle generation and repair UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2024-07-23 US disclosed
US-20240190952-A1 IL-18 Binding Protein (IL-18BP) and Antibodies for Treating Inflammatory Diseases AB2 BIO SA (CH) 2024-06-13 US disclosed
US-20240181015-A1 EFFECT OF GHRH ANTAGONISTS IN DIABETES AND OBESITY AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. (US) 2024-06-06 US disclosed
US-20240166770-A1 COMPOSITIONS AND METHODS FOR INHIBITION OF CELL-PENETRATING ANTIBODIES YALE UNIVERSITY 2024-05-23 US disclosed
EP-4367086-A2 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING VIRAL INFECTIONS University of Georgia Research Foundation, Inc. (US) 2024-05-15 EP disclosed
US-20240150311-A1 COMPOSITIONS AND METHODS FOR INHIBITING IDO1 AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. 2024-05-09 US disclosed
US-11926663-B2 IL-18 binding protein (IL-18BP) and antibodies in inflammatory diseases AB2 BIO SA (CH) 2024-03-12 US disclosed
US-5043441-A Enhance penetration of active materials through skin WHITBY RESEARCH, INC. (US) 1991-08-27 US disclosed
US-5034386-A Fungicides WHITBY RESEARCH, INC. (US) 1991-07-23 US disclosed
US-4886783-A Penetration enhancers for transdermal delivery of systemic agents NELSON RESEARCH & DEVELOPMENT CO. (US) 1989-12-12 US disclosed
US-4886545-A IMPROVE DELIVERY OF PLANT NUTRIENTS NELSON RESEARCH & DEVELOPMENT COMPANY (US) 1989-12-12 US disclosed
EP-0257086-A4 Skinpenetration enhancing compositions. NELSON RES & DEV COMPANY (US) 1989-04-12 EP disclosed
EP-0268218-A2 Penetration enhancers for transdermal delivery of systemic agents WHITBY RESEARCH, Inc. (US) 1988-05-25 EP disclosed
EP-0257086-A1 Skinpenetration enhancing compositions. NELSON RES & DEV (US) 1988-03-02 EP disclosed
US-4716060-A ACYCLIC OR HETEROCYCLIC TERTIARY AMIDE RAJADHYAKSHA VITHAL J (US) 1987-12-29 US disclosed
WO-1987004594-A1 COMPOSITIONS COMPRISING 1-SUBSTITUTED AZACYCLOALKANES AND THEIR USES NELSON RESEARCH AND DEVELOPMENT COMPANY (US) 1987-08-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES CNR2, CNR1, FAAH LMNA 3441/4885L3MBTL1 4862/4885MEN1 4840/4885
US-20240166770-A1 COMPOSITIONS AND METHODS FOR INHIBITION OF CELL-PENETRATING ANTIBODIES SLC29A1, SLC29A2, SLC7A1 LMNA 1063/4885L3MBTL1 2097/4885MEN1 1409/4885
US-12042507-B2 Compositions and methods of modulating HIF-2A to improve muscle generation and repair HIF1A, HIF1AN, MYLK2 LMNA 621/4885L3MBTL1 3032/4885MEN1 4701/4885
US-20240150311-A1 COMPOSITIONS AND METHODS FOR INHIBITING IDO1 IDO1, IDO2, PYGM LMNA 2265/4885L3MBTL1 3113/4885MEN1 4015/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.