Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 3/20 | 0.62 |
| ▸ | USP30 | Q70CQ3 | 12/20 | 0.60 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.59 |
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17643828 | 1.00 | UCHL1 (0.62) | UCHL1USP30MKNK1OTUD7BKDR | |
| SCHEMBL17643702 | 0.90 | USP30 (0.60) | UCHL1USP30MKNK1OTUD7B | |
| SCHEMBL17631844 | 0.90 | USP30 (0.60) | UCHL1USP30MKNK1OTUD7B | |
| SCHEMBL23452856 | 0.90 | USP30 (0.60) | UCHL1USP30MKNK1OTUD7B | |
| SCHEMBL17643662 | 0.86 | UCHL1 (0.48) | UCHL1USP30MKNK1OTUD7B | |
| SCHEMBL30513301 | 0.86 | UCHL1 (0.48) | UCHL1USP30MKNK1OTUD7B | |
| SCHEMBL17632466 | 0.82 | OTUD7B (0.54) | UCHL1USP30MKNK1OTUD7B | |
| SCHEMBL23403452 | 0.82 | OTUD7B (0.54) | UCHL1USP30MKNK1OTUD7B | |
| SCHEMBL19281675 | 0.80 | UCHL1 (0.66) | UCHL1USP30MKNK1OTUD7BKDR | |
| SCHEMBL17643843 | 0.80 | UCHL1 (0.66) | UCHL1USP30MKNK1OTUD7BKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |