Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTUD7B | Q6GQQ9 | 8/20 | 0.54 |
| ▸ | USP30 | Q70CQ3 | 9/20 | 0.51 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632466 | 1.00 | OTUD7B (0.54) | OTUD7BUSP30UCHL1MKNK1 | |
| SCHEMBL17643662 | 0.86 | UCHL1 (0.48) | OTUD7BUSP30UCHL1MKNK1 | |
| SCHEMBL30513301 | 0.86 | UCHL1 (0.48) | OTUD7BUSP30UCHL1MKNK1 | |
| SCHEMBL17632124 | 0.82 | OTUD7B (0.76) | OTUD7BUSP30UCHL1MKNK1 | |
| SCHEMBL25052368 | 0.82 | OTUD7B (0.76) | OTUD7BUSP30UCHL1MKNK1 | |
| SCHEMBL17643828 | 0.82 | UCHL1 (0.62) | OTUD7BUSP30UCHL1MKNK1 | |
| SCHEMBL17631690 | 0.82 | UCHL1 (0.62) | OTUD7BUSP30UCHL1MKNK1 | |
| SCHEMBL17631844 | 0.74 | USP30 (0.60) | OTUD7BUSP30UCHL1MKNK1 | |
| SCHEMBL23452856 | 0.74 | USP30 (0.60) | OTUD7BUSP30UCHL1MKNK1 | |
| SCHEMBL17643702 | 0.74 | USP30 (0.60) | OTUD7BUSP30UCHL1MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3828179-A1 | CYANOPYRROLIDINES AS DUB MODULATORS | Mission Therapeutics Limited (GB) | 2021-06-02 | — | — | EP | disclosed |