Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 8/20 | 0.42 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 2/20 | 0.37 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | WNT1 | P04628 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17631623 | 0.93 | CHEK1 (0.41) | OTUD7BUSP30UCHL1WNT1GSK3B | |
| SCHEMBL17631924 | 0.91 | USP30 (0.42) | OTUD7BUSP30UCHL1CDK8CHEK1 | |
| SCHEMBL17631742 | 0.88 | USP30 (0.44) | USP30UCHL1FYNCYP3A4CHEK1 | |
| SCHEMBL17632483 | 0.88 | USP30 (0.42) | OTUD7BUSP30UCHL1FYNCHEK1 | |
| SCHEMBL17632036 | 0.88 | USP30 (0.50) | USP30UCHL1CHEK1 | |
| SCHEMBL17632150 | 0.86 | USP30 (0.43) | USP30UCHL1CHEK1 | |
| SCHEMBL17632442 | 0.86 | CHEK1 (0.44) | USP30UCHL1GSK3BCHEK1 | |
| SCHEMBL17631758 | 0.86 | WNT1 (0.37) | USP30UCHL1PIK3CAWNT1GSK3B | |
| SCHEMBL17632087 | 0.85 | WNT1 (0.36) | USP30UCHL1PIK3CAWNT1GSK3B | |
| SCHEMBL17632503 | 0.85 | USP30 (0.42) | USP30UCHL1FYNDYRK1ATNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |