Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA4 | P22748 | 3/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 3/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 4/20 | 0.33 |
| ▸ | CHUK | O15111 | 4/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CDK2AP1 | O14519 | 1/20 | 0.32 |
| ▸ | WNT1 | P04628 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17631830 | 0.88 | USP30 (0.40) | USP30UCHL1CHEK1CDK2AP1WNT1 | |
| SCHEMBL17632491 | 0.87 | CHEK1 (0.42) | USP30UCHL1CHEK1CDK2AP1WNT1 | |
| SCHEMBL17632487 | 0.87 | USP30 (0.41) | USP30UCHL1CHEK1CDK2AP1WNT1 | |
| SCHEMBL17632016 | 0.86 | USP30 (0.40) | USP30UCHL1CHEK1CDK2AP1WNT1 | |
| SCHEMBL17632036 | 0.86 | USP30 (0.50) | USP30UCHL1CHEK1 | |
| SCHEMBL17632604 | 0.85 | UCHL1 (0.43) | USP30UCHL1CHEK1CDK2AP1WNT1 | |
| SCHEMBL17632047 | 0.85 | USP30 (0.41) | USP30UCHL1CHEK1AKT1CDK2AP1 | |
| SCHEMBL17631715 | 0.84 | CHEK1 (0.42) | USP30UCHL1CHEK1CDK9WNT1 | |
| SCHEMBL17632265 | 0.84 | USP30 (0.42) | USP30UCHL1CHEK1 | |
| SCHEMBL17632415 | 0.84 | CHEK1 (0.41) | USP30UCHL1CHEK1CDK2AP1WNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |