Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 12/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632318 | 0.88 | GRM5 (0.41) | — | |
| SCHEMBL17631750 | 0.87 | GRM5 (0.38) | — | |
| SCHEMBL17632587 | 0.86 | NPC1 (0.40) | F10NPC1RAB9A | |
| SCHEMBL17631404 | 0.86 | TLR9 (0.39) | NPC1RAB9A | |
| SCHEMBL17632462 | 0.85 | FASN (0.35) | F10 | |
| SCHEMBL17632465 | 0.85 | GRM5 (0.43) | F10ROCK2NPC1RAB9A | |
| SCHEMBL17631931 | 0.84 | GRM5 (0.43) | F10NPC1RAB9A | |
| SCHEMBL17631972 | 0.81 | GRM5 (0.51) | — | |
| SCHEMBL17632538 | 0.81 | ALDH1A1 (0.51) | KDM4EROCK2NPC1CYP2C19RAB9A | |
| SCHEMBL17632125 | 0.80 | GRM5 (0.40) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |