Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.43 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | F12 | P00748 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632587 | 0.91 | NPC1 (0.40) | GRM5FASNF12NPC1RAB9A | |
| SCHEMBL17631931 | 0.88 | GRM5 (0.43) | GRM5FASNF12NPC1RAB9A | |
| SCHEMBL17632276 | 0.85 | F10 (0.41) | NPC1RAB9AF10ROCK2 | |
| SCHEMBL17632125 | 0.84 | GRM5 (0.40) | GRM5F12NPC1RAB9AKMT2A | |
| SCHEMBL17632318 | 0.83 | GRM5 (0.41) | GRM5FASN | |
| SCHEMBL17631750 | 0.82 | GRM5 (0.38) | GRM5 | |
| SCHEMBL17631404 | 0.81 | TLR9 (0.39) | GRM5NPC1RAB9A | |
| SCHEMBL17632462 | 0.81 | FASN (0.35) | GRM5FASNF10 | |
| SCHEMBL17631972 | 0.77 | GRM5 (0.51) | GRM5 | |
| SCHEMBL17632538 | 0.76 | ALDH1A1 (0.51) | NPC1RAB9AKMT2AROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |