SCHEMBL17632736

SCHEMBL17632736

C[C@H]1[C@@H](C(=O)O)CCN1C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 1/20 0.31
MAPT P10636 1/20 0.30
SLC1A2 P43004 1/20 0.30
ACE P12821 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20594652 1.00 GABRR1 (0.31) GABRR1MAPTSLC1A2ACE
SCHEMBL20594793 1.00 GABRR1 (0.31) GABRR1MAPTSLC1A2ACE
SCHEMBL28266603 0.88 ACE (0.41) MAPTACE
SCHEMBL18283617 0.88 ACE (0.41) MAPTACE
SCHEMBL5195673 0.86
SCHEMBL20594444 0.83 EPHX1 (0.41)
SCHEMBL3604753 0.83 EPHX1 (0.41)
SCHEMBL20594697 0.83 EPHX1 (0.41)
SCHEMBL20899353 0.80 AR (0.39)
SCHEMBL25052846 0.77 GAA (0.40) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11993595-B2 Compounds MISSION THERAPEUTICS LIMITED (GB) 2024-05-28 US disclosed
US-20230052191-A1 NOVEL COMPOUNDS MISSION THERAPEUTICS LTD (GB) 2023-02-16 US disclosed
EP-3828179-A1 CYANOPYRROLIDINES AS DUB MODULATORS Mission Therapeutics Limited (GB) 2021-06-02 EP disclosed
US-20200369658-A1 NOVEL COMPOUNDS MISSION THERAPEUTICS LTD (GB) 2020-11-26 US disclosed
US-10774078-B2 Compounds MISSION THERAPEUTICS LTD (GB) 2020-09-15 US disclosed
EP-3197883-B1 NOVEL COMPOUNDS MISSION THERAPEUTICS LTD (GB) 2020-03-18 EP disclosed
CN-107001339-B Novel compounds 特殊治疗有限公司 2020-03-17 CN disclosed
US-20190330202-A1 NOVEL COMPOUNDS MISSION THERAPEUTICS LTD (GB) 2019-10-31 US disclosed
US-10392380-B2 Compounds MISSION THERAPEUTICS LIMITED (GB) 2019-08-27 US disclosed
US-20180162852-A1 NOVEL COMPOUNDS MISSION THERAPEUTICS LIMITED 2018-06-14 US disclosed
US-9926307-B2 Compounds MISSION THERAPEUTICS LTD (GB) 2018-03-27 US disclosed
US-20170247365-A1 NOVEL COMPOUNDS MISSION THERAPEUTICS LTD (GB) 2017-08-31 US disclosed
EP-3197883-A1 NOVEL COMPOUNDS Mission Therapeutics Limited (GB) 2017-08-02 EP disclosed
WO-2016046530-A1 NOVEL COMPOUNDS MISSION THERAPEUTICS LTD (GB) 2016-03-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10774078-B2 Compounds UCHL1, UCHL3, UCHL5 GABRR1 2710/4885MAPT 2227/4885SLC1A2 4458/4885
US-20180162852-A1 NOVEL COMPOUNDS UCHL1, UCHL3, UCHL5 GABRR1 2849/4885MAPT 2428/4885SLC1A2 4537/4885
US-10392380-B2 Compounds UCHL1, UCHL3, UCHL5 GABRR1 2710/4885MAPT 2227/4885SLC1A2 4458/4885
US-11993595-B2 Compounds UCHL1, UCHL3, UCHL5 GABRR1 2710/4885MAPT 2227/4885SLC1A2 4458/4885
US-20200369658-A1 NOVEL COMPOUNDS UCHL1, UCHL3, UCHL5 GABRR1 2849/4885MAPT 2428/4885SLC1A2 4537/4885
US-20190330202-A1 NOVEL COMPOUNDS UCHL1, UCHL3, UCHL5 GABRR1 2849/4885MAPT 2428/4885SLC1A2 4537/4885
US-20170247365-A1 NOVEL COMPOUNDS UCHL1, UCHL3, UCHL5 GABRR1 2849/4885MAPT 2428/4885SLC1A2 4537/4885
US-20230052191-A1 NOVEL COMPOUNDS UCHL1, UCHL3, UCHL5 GABRR1 2849/4885MAPT 2428/4885SLC1A2 4537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.