Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 19/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632053 | 0.90 | CHEK1 (0.40) | CHEK1USP30 | |
| SCHEMBL17631680 | 0.90 | CHEK1 (0.40) | CHEK1USP30 | |
| SCHEMBL17632087 | 0.89 | WNT1 (0.36) | CHEK1USP30 | |
| SCHEMBL17632016 | 0.86 | USP30 (0.40) | CHEK1USP30 | |
| SCHEMBL17631994 | 0.85 | KDM1A (0.39) | USP30 | |
| SCHEMBL17632491 | 0.85 | CHEK1 (0.42) | CHEK1USP30 | |
| SCHEMBL17632483 | 0.84 | USP30 (0.42) | CHEK1KCNH2USP30 | |
| SCHEMBL17631830 | 0.84 | USP30 (0.40) | CHEK1USP30 | |
| SCHEMBL17632503 | 0.83 | USP30 (0.42) | CHEK1KCNH2USP30 | |
| SCHEMBL17632415 | 0.83 | CHEK1 (0.41) | CHEK1KCNH2USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |