Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HTR6 | P50406 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1156314 | 0.99 | ALDH1A1 (0.50) | ALDH1A1HTR6MAPTRAPGEF4LMNA | |
| SCHEMBL1580931 | 0.93 | ALDH1A1 (0.45) | ALDH1A1HTR6MAPTRAPGEF4LMNA | |
| Hydrochloric Acid SCHEMBL1156844 | 0.92 | ALDH1A1 (0.44) | ALDH1A1HTR6MAPTRAPGEF4LMNA | |
| SCHEMBL1580431 | 0.89 | LMNA (0.43) | ALDH1A1HTR6MAPTRAPGEF4LMNA | |
| SCHEMBL1580766 | 0.89 | HTR6 (0.43) | ALDH1A1HTR6MAPTL3MBTL1ELAVL1 | |
| SCHEMBL1581101 | 0.89 | HTR6 (0.45) | HTR6MAPTPKMPOLBL3MBTL1 | |
| SCHEMBL1156820 | 0.89 | EGFR (0.44) | ALDH1A1HTR6MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL1156502 | 0.88 | LMNA (0.42) | ALDH1A1HTR6MAPTRAPGEF4LMNA | |
| SCHEMBL1763133 | 0.88 | PLAU (0.42) | ALDH1A1HTR6MAPTRAPGEF4MEN1 | |
| Hydrochloric Acid SCHEMBL1156349 | 0.88 | HTR6 (0.42) | ALDH1A1HTR6MAPTL3MBTL1ELAVL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9186411-B2 | Pharmaceutical composition | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-11-17 | — | — | US | disclosed |
| US-20130261156-A1 | PHARMACEUTICAL COMPOSITION | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-10-03 | — | — | US | disclosed |
| EP-2564833-A1 | Photostabilized pharmaceutical composition | Takeda Pharmaceutical Company Limited (JP) | 2013-03-06 | — | — | EP | disclosed |
| US-20110124687-A1 | PHARMACEUTICAL COMPOSITION | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124687-A1 | PHARMACEUTICAL COMPOSITION | CYP2C19, MLST8, CYP3A43 | ALDH1A1 1146/4885HTR6 1727/4885MAPT 539/4885 |
| US-20130261156-A1 | PHARMACEUTICAL COMPOSITION | CYP2C19, MLST8, CYP3A43 | ALDH1A1 1146/4885HTR6 1727/4885MAPT 539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.