Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1762949 | 1.00 | ALDH1A1 (0.33) | ALDH1A1MAPK1TDP1 | |
| SCHEMBL1762947 | 1.00 | ALDH1A1 (0.33) | ALDH1A1MAPK1TDP1 | |
| SCHEMBL22048285 | 0.78 | — | — | |
| SCHEMBL4150294 | 0.73 | — | — | |
| SCHEMBL19539825 | 0.69 | — | — | |
| SCHEMBL13354236 | 0.67 | ALDH1A1 (0.33) | ALDH1A1MAPK1TDP1 | |
| SCHEMBL6506120 | 0.67 | — | — | |
| SCHEMBL12311430 | 0.67 | — | — | |
| SCHEMBL23263135 | 0.66 | ALDH1A1 (0.32) | ALDH1A1MAPK1TDP1 | |
| SCHEMBL4158148 | 0.66 | KMT2A (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8759541-B2 | Chiral acyclic diaminocarbene ligands, precursors therefore and their use in organic synthesis reactions | THADANI AVINASH N (CA) | 2014-06-24 | — | — | US | disclosed |
| US-20110118475-A1 | CHIRAL ACYCLIC DIAMINOCARBENE LIGANDS, PRECURSORS THEREFORE AND THEIR USE IN ORGANIC SYNTHESIS REACTIONS | THADANI AVINASH N | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118475-A1 | CHIRAL ACYCLIC DIAMINOCARBENE LIGANDS, PRECURSORS THEREFORE AND THEIR USE IN ORGANIC SYNTHESIS REACTIONS | AOC1, ODC1, AMD1 | ALDH1A1 428/4885MAPK1 1165/4885TDP1 4672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.