Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | MAPT | P10636 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | PKM | P14618 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29393290 | 0.87 | ALDH1A1 (1.00) | KMT2AMAPTALDH1A1MEN1PKM | |
| SCHEMBL28273654 | 0.82 | KMT2A (0.62) | KMT2AMAPTALDH1A1MEN1PKM | |
| SCHEMBL13297964 | 0.80 | RAB9A (0.69) | KMT2AALDH1A1MEN1LMNARAB9A | |
| SCHEMBL29941863 | 0.77 | RAB9A (0.59) | KMT2AALDH1A1MEN1LMNARAB9A | |
| SCHEMBL11199870 | 0.75 | ALDH1A1 (0.52) | KMT2AMAPTALDH1A1MEN1PKM | |
| SCHEMBL10403761 | 0.75 | ALDH1A1 (0.58) | KMT2AMAPTALDH1A1MEN1PKM | |
| SCHEMBL10404254 | 0.75 | ALDH1A1 (0.58) | KMT2AMAPTALDH1A1MEN1PKM | |
| SCHEMBL10403758 | 0.75 | ALDH1A1 (0.58) | KMT2AMAPTALDH1A1MEN1PKM | |
| SCHEMBL10404255 | 0.74 | ALDH1A1 (0.57) | KMT2AMAPTALDH1A1MEN1PKM | |
| SCHEMBL17633758 | 0.74 | ALDH1A1 (0.69) | KMT2AMAPTALDH1A1MEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197476-A1 | USE OF CYSTEAMINE IN TREATING INFECTIONS CAUSED BY YEASTS/MOULDS | Novabiotics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046524-A1 | USE OF CYSTEAMINE IN TREATING INFECTIONS CAUSED BY YEASTS/MOULDS | NOVABIOTICS LIMITED (GB) | 2016-03-31 | — | — | WO | disclosed |