SCHEMBL11199870

SCHEMBL11199870

Cc1ccc(S(=O)(=O)[NH+]([O-])CCSc2ccccn2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 13/20 0.52
LMNA P02545 4/20 0.52
SMN1; SMN2 Q16637 3/20 0.48
NPC1 O15118 3/20 0.48
RAB9A P51151 3/20 0.48
HPGD P15428 2/20 0.47
KDM4E B2RXH2 1/20 0.47
ALOX15 P16050 1/20 0.47
HSD17B10 Q99714 1/20 0.47
KMT2A Q03164 4/20 0.46
MAPT P10636 3/20 0.46
GAA P10253 1/20 0.46
MEN1 O00255 2/20 0.45
PKM P14618 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
POLB P06746 1/20 0.45
USP2 O75604 1/20 0.43
TSHR P16473 1/20 0.43
HTT P42858 1/20 0.43
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17633933 0.75 KMT2A (0.77) ALDH1A1LMNASMN1; SMN2NPC1RAB9A
SCHEMBL10330811 0.70 DNMT1 (0.53) ALDH1A1LMNASMN1; SMN2NPC1RAB9A
SCHEMBL10767199 0.69 ALDH1A1 (0.52) ALDH1A1LMNASMN1; SMN2NPC1RAB9A
SCHEMBL6987050 0.69 ALDH1A1 (0.51) ALDH1A1LMNASMN1; SMN2NPC1RAB9A
SCHEMBL12744425 0.68 ALDH1A1 (0.50) ALDH1A1LMNASMN1; SMN2NPC1RAB9A
SCHEMBL10404244 0.68 ALDH1A1 (0.50) ALDH1A1LMNASMN1; SMN2NPC1RAB9A
SCHEMBL7140573 0.67 ALDH1A1 (0.49) ALDH1A1LMNASMN1; SMN2NPC1RAB9A
SCHEMBL10404243 0.67 ALDH1A1 (0.49) ALDH1A1LMNASMN1; SMN2NPC1RAB9A
SCHEMBL10403758 0.67 ALDH1A1 (0.58) ALDH1A1LMNASMN1; SMN2NPC1RAB9A
SCHEMBL10403761 0.67 ALDH1A1 (0.58) ALDH1A1LMNASMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230404947-A1 COMPOSITIONS, METHODS OF TREATMENT, AND CONTAINERS INCLUDING COMPOSITIONS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2023-12-21 US disclosed
US-20230338310-A1 ANTI-VIRAL THERAPY NOVABIOTICS LIMITED (GB) 2023-10-26 US disclosed
US-11771665-B2 Compositions, methods of treatment, and containers including compositions UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2023-10-03 US disclosed
EP-4157247-A1 ANTI-VIRAL THERAPY Novabiotics Limited (GB) 2023-04-05 EP disclosed
US-20220347126-A1 COMPOSITIONS, METHODS OF TREATMENT, AND CONTAINERS INCLUDING COMPOSITIONS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2022-11-03 US disclosed
US-11369568-B2 Microparticles comprising a sulphur-containing compound NOVABIOTICS LIMITED (GB) 2022-06-28 US disclosed
WO-2021240145-A1 ANTI-VIRAL THERAPY NOVABIOTICS LIMITED (GB) 2021-12-02 WO disclosed
WO-2021203136-A1 METHODS FOR TREATING HYPERPIGMENTATION AND COMPOSITIONS FOR SAME CHEMISTRYRX (US) 2021-10-07 WO disclosed
US-20210299019-A1 METHODS FOR TREATING HYPERPIGMENTATION AND COMPOSITIONS FOR SAME CHEMISTRYRX (US) 2021-09-30 US disclosed
US-10905660-B2 Microparticles NOVABIOTICS LIMITED (GB) 2021-02-02 US disclosed
WO-2016198842-A1 AN AMINO THIOL FOR USE IN THE TREATMENT OF AN INFECTION CAUSED BY THE BACTERIUM MYCOBACTERIUM SPP. NOVABIOTICS LIMITED (GB) 2016-12-15 WO disclosed
US-20160102052-A1 Use of Cysteamine in Treating Infections caused by Yeasts/Moulds NOVABIOTICS LIMITED (GB) 2016-04-14 US disclosed
WO-2016046524-A1 USE OF CYSTEAMINE IN TREATING INFECTIONS CAUSED BY YEASTS/MOULDS NOVABIOTICS LIMITED (GB) 2016-03-31 WO disclosed
US-4394520-A SKIN DISORDERS SOCIETE ANONYME DITE: L'OREAL (FR) 1983-07-19 US disclosed
US-4204064-A FOR TREATMENT OF SKIN OR SCALP L'OREAL (FR) 1980-05-20 US disclosed
US-4139635-A Cysteamine derivatives for oral treatment of seborrhea L'OREAL (FR) 1979-02-13 US disclosed
US-4085217-A DERIVATIVES OF CYSTEINE OR CYSTEAMINE L'OREAL (FR) 1978-04-18 US disclosed
US-4035492-A Oral treatment of seborrhea with cysteamine derivatives L'OREAL (FR) 1977-07-12 US disclosed
US-3976781-A SULFUR CONTAINING AMINES L'OREAL (FR) 1976-08-24 US disclosed
US-3950542-A Cysteamine derivatives for oral treatment of seborrhea L'OREAL (FR) 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230338310-A1 ANTI-VIRAL THERAPY MAVS, HAVCR2, IRF3 ALDH1A1 2213/4885LMNA 3342/4885SMN1; SMN2 2770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.