SCHEMBL176344

SCHEMBL176344

Cc1cc(O)c(C(C)(C)C)c(C(C)(C)C)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.60
SMN1; SMN2 Q16637 4/20 0.60
CA2 P00918 4/20 0.60
TYR P14679 2/20 0.60
POLB P06746 1/20 0.60
HSPA5 P11021 1/20 0.48
ALOX15 P16050 5/20 0.48
CYP1A2 P05177 2/20 0.48
MAPT P10636 2/20 0.48
KDM4E B2RXH2 1/20 0.48
ATP2A2 P16615 1/20 0.48
ATP2A3 Q93084 1/20 0.48
CYP2C9 P11712 4/20 0.47
HIF1A Q16665 3/20 0.47
CYP2C19 P33261 3/20 0.47
SELL P14151 1/20 0.44
SELP P16109 1/20 0.44
SELE P16581 1/20 0.44
ACHE P22303 1/20 0.44
TSHR P16473 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38657300 1.00 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2CA2TYRPOLB
SCHEMBL9742612 0.85 SELL (0.52) ALDH1A1SMN1; SMN2CA2TYRPOLB
SCHEMBL394948 0.79 SELL (0.46) ALDH1A1SMN1; SMN2CA2TYRPOLB
SCHEMBL3910478 0.79 ALDH1A1 (0.62) ALDH1A1SMN1; SMN2CA2TYRPOLB
SCHEMBL20134480 0.79 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2CA2TYRPOLB
SCHEMBL1374664 0.79 ALDH1A1 (0.77) ALDH1A1SMN1; SMN2CA2TYRPOLB
SCHEMBL28487119 0.77 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2CA2TYRPOLB
SCHEMBL28613619 0.77 ALOX15 (0.54) ALDH1A1SMN1; SMN2CA2TYRPOLB
SCHEMBL11954794 0.76 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2CA2TYRPOLB
SCHEMBL9820540 0.76 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2CA2TYRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4195030-A Preparation of monomeric organosilicon esters BAUSCH & LOMB INCORPORATED (US) 1980-03-25 US claimed
EP-3825145-A1 TIRE RUBBER COMPOSITION AND TIRE Sumitomo Rubber Industries, Ltd. (JP) 2021-05-26 EP disclosed
CN-112679635-A Preparation method of supported metallocene catalyst and catalyst prepared by same 中国石油化工股份有限公司 2021-04-20 CN disclosed
US-9403297-B2 Method for producing molded parts, especially for use in automobile manufacture, and corresponding appropriate films comprising a coating BASF COATINGS GMBH (DE) 2016-08-02 US disclosed
EP-1737654-B1 FLEXIBLE LAMINATED COMPOSITE COMPRISING A SUBSTRATE AND A LAYER APPLIED THERETO WHICH CONSISTS OF A CURABLE LACQUER KARL WÖRWAG LACK UND FARBENFABRIK GMBH & CO KG (DE) 2015-12-09 EP disclosed
EP-1723194-B1 RADIATION CURABLE COMPOSITE LAYERED PLATE OR FILM AND ITS USE FOR COATING MOULDED ARTICLES BASF SE (DE) 2015-01-07 EP disclosed
US-8337649-B2 Repair film and use thereof BASF COATINGS GMBH (DE) 2012-12-25 US disclosed
US-8334052-B2 Radiation hardened composite layer plate or film BASF AKTIENGESELLSCHAFT (DE) 2012-12-18 US disclosed
EP-1171298-B2 RADIATION-CURABLE COMPOSITE BOARD OR FILM BASF SE (DE) 2011-11-30 EP disclosed
US-8053065-B2 Flexible layer composite comprising a support and a layer of curable surface coating composition applied thereto Karl WorKwag Lack- und Farbenfabrik GmbH & Co. KG (DE) 2011-11-08 US disclosed
JP-2005276699-A COVERING MATERIAL COMPOSITE FOR ELECTRIC WIRE ASAHI DENKA KOGYO KK 2005-10-06 JP disclosed
US-20040224162-A1 self-supporting multilayers comprising a coloring interlayer between a substrate and outer layer, used as coatings having photostability, wear, scratch and aging resistance BASF AKTIENGESELLSCHAFT (DE) 2004-11-11 US disclosed
US-6777089-B1 OUTER LAYER IS BINDER WITH A GLASS TRANSITION TEMPERATURE ABOVE 40 C.; CURABLE UNSATURATED OR ACRYLATED RESIN; POLYURETHANE; THERMOPLASTIC INTERLAYER; AUTOMOBILE MOLDINGS BASF AKTIENGESELLSCHAFT (DE) 2004-08-17 US disclosed
EP-1171298-B1 RADIATION-CURABLE COMPOSITE BOARD OR FILM BASF AG (DE) 2004-08-11 EP disclosed
EP-0852009-B1 BUFFER COMPOSITION FOR REAGENTS FOR IMMUNOASSAY ABBOTT LAB (US) 2002-08-28 EP disclosed
EP-0486279-B2 Process for removing acidic impurities from alkoxysilanes SHINETSU CHEMICAL CO (JP) 1999-12-01 EP disclosed
US-5247117-A Neutralization with sterically hindered alcohols or amines, distillation SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-09-21 US disclosed
EP-0498384-A2 Integrally molded composites and method therefor NIPPON ZEON CO., LTD. (JP) 1992-08-12 EP disclosed
EP-0486279-A1 Process for removing acidic impurities from alkoxysilanes SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-05-20 EP disclosed
US-4113792-A ACRYLIC POLYMERS, CHLOROSULFONATED POLYETHYLENE, INITIATORS NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1978-09-12 US disclosed