Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.52 |
| ▸ | TYR | P14679 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | MIF | P14174 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.50 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11034207 | 0.87 | ALDH1A1 (0.52) | ALDH1A1ALOX15TYRLMNACYP2C9 | |
| SCHEMBL9743218 | 0.85 | GABRA1 (0.50) | ALDH1A1ALOX15TYRLMNACYP2C9 | |
| SCHEMBL9652141 | 0.80 | ALDH1A1 (0.50) | ALDH1A1ALOX15TYRLMNACYP2C9 | |
| SCHEMBL38657300 | 0.79 | ALDH1A1 (0.60) | ALDH1A1ALOX15TYRLMNACYP2C9 | |
| SCHEMBL28487119 | 0.79 | ALDH1A1 (0.48) | ALDH1A1ALOX15TYRLMNACYP2C9 | |
| SCHEMBL23387403 | 0.79 | ALOX15 (0.45) | ALDH1A1ALOX15TYRLMNACYP2C9 | |
| SCHEMBL176344 | 0.79 | ALDH1A1 (0.60) | ALDH1A1ALOX15TYRLMNACYP2C9 | |
| SCHEMBL8611108 | 0.78 | CA2 (0.54) | ALDH1A1ALOX15TYRLMNACYP2C9 | |
| SCHEMBL9820540 | 0.78 | ALDH1A1 (0.59) | ALDH1A1ALOX15TYRLMNACYP2C9 | |
| SCHEMBL18688896 | 0.77 | ALDH1A1 (0.46) | ALDH1A1ALOX15TYRLMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127392-A1 | ECKOL DERIVATIVES, METHODS OF SYNTHESIS AND USES THEREOF | Phloronol, Inc. | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127392-A1 | ECKOL DERIVATIVES, METHODS OF SYNTHESIS AND USES THEREOF | MGLL, PNLIP, ECHS1 | ALDH1A1 1648/4885ALOX15 54/4885TYR 1366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.