SCHEMBL176350

SCHEMBL176350

C=CC(=O)OCC(COC(=O)C(=C)C)OC(=O)C(=C)C

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 10/20 0.50
HPGD P15428 1/20 0.37
ALDH1A1 P00352 5/20 0.36
TP53 P04637 3/20 0.36
HIF1A Q16665 3/20 0.36
CYP3A4 P08684 2/20 0.36
HSD17B10 Q99714 1/20 0.36
THRB P10828 1/20 0.36
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL700973 0.93 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL18567468 0.92 TSHR (0.49) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL4464394 0.90 TSHR (0.53) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL12828658 0.89 TSHR (0.46) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28397783 0.89 TSHR (0.49) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL336611 0.89 TSHR (0.49) TSHR
SCHEMBL21976107 0.88 TSHR (0.52) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL35507 0.88 TSHR (0.63) TSHRALDH1A1THRB
SCHEMBL18080879 0.87 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL10269885 0.86 TSHR (0.44) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025121154-A1 CURABLE COMPOSITION, CURED ARTICLE, LAMINATE, OPTICAL ARTICLE, LENS, AND SPECTACLES 株式会社トクヤマ 2025-06-12 WO disclosed
EP-2853386-B1 SUBSTRATE AND TOUCH PANEL MEMBER USING SAME TORAY INDUSTRIES (JP) 2017-10-25 EP disclosed
US-9690197-B2 Negative-type photosensitive white composition for touch panel, touch panel and touch panel production method TORAY INDUSTRIES, INC. (JP) 2017-06-27 US disclosed
US-20160161847-A1 NEGATIVE-TYPE PHOTOSENSITIVE WHITE COMPOSITION FOR TOUCH PANEL, TOUCH PANEL AND TOUCH PANEL PRODUCTION METHOD TORAY INDUSTRIES, INC. (JP) 2016-06-09 US disclosed
EP-2130817-B1 Polymerizable Type II photoinitiators and curable compositions AGFA GRAPHICS NV (BE) 2016-01-06 EP disclosed
US-20150125680-A1 SUBSTRATE AND TOUCH PANEL MEMBER USING SAME TORAY INDUSTRIES, INC. (JP) 2015-05-07 US disclosed
EP-2853386-A1 SUBSTRATE AND TOUCH PANEL MEMBER USING SAME Toray Industries, Inc. (JP) 2015-04-01 EP disclosed
US-8389769-B2 Polymerizable type II photoinitiators and curable compositions AGFA GRAPHICS NV (BE) 2013-03-05 US disclosed
US-8389769-B2 Polymerizable type II photoinitiators and curable compositions AGFA GRAPHICS NV (BE) 2013-03-05 US disclosed
US-8389769-B2 Polymerizable type II photoinitiators and curable compositions AGFA GRAPHICS NV (BE) 2013-03-05 US disclosed
US-20110063388-A1 POLYMERIZABLE TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2011-03-17 US disclosed
US-20110063388-A1 POLYMERIZABLE TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2011-03-17 US disclosed
US-20110063388-A1 POLYMERIZABLE TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2011-03-17 US disclosed
US-7777080-B2 Carboxylic acid derivatives containing phosphorous groups and organically polymerizable groups FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2010-08-17 US disclosed
WO-2009147057-A1 POLYMERIZABLE TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2009-12-10 WO disclosed
EP-2130817-A1 Polymerizable Type II photoinitiators and curable compositions AGFA Graphics NV (BE) 2009-12-09 EP disclosed
US-20060142515-A1 Carboxylic acid derivatives containing phosphorous groups and organically polymerisable groups FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2006-06-29 US disclosed
EP-1537130-A1 CARBOXYLIC ACID DERIVATIVES CONTAINING PHOSPHOROUS GROUPS AND ORGANICALLY POLYMERISABLE GROUPS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2005-06-08 EP disclosed
WO-2004026884-A1 CARBOXYLIC ACID DERIVATIVES CONTAINING PHOSPHOROUS GROUPS AND ORGANICALLY POLYMERISABLE GROUPS FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2004-04-01 WO disclosed
EP-0588533-B1 Printed thermoplastic resin products and method for printing such products HAYAKAWA RUBBER (JP) 1998-08-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110063388-A1 POLYMERIZABLE TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS CCNH, CRKL, ERH TSHR 2470/4885HPGD 2084/4885ALDH1A1 1584/4885
US-20060142515-A1 Carboxylic acid derivatives containing phosphorous groups and organically polymerisable groups CA6, PGD, PHGDH TSHR 4722/4885HPGD 365/4885ALDH1A1 711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.