Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17635150 | 1.00 | TSHR (0.34) | TSHRMGLLGLA | |
| SCHEMBL978470 | 0.85 | MGLL (0.33) | MGLL | |
| SCHEMBL612317 | 0.85 | MGLL (0.33) | MGLL | |
| SCHEMBL15991702 | 0.84 | KMT2A (0.38) | TSHRMGLL | |
| SCHEMBL916283 | 0.83 | MGLL (0.33) | TSHRMGLLGLA | |
| SCHEMBL917047 | 0.82 | MGLL (0.32) | MGLL | |
| SCHEMBL17634453 | 0.82 | MGLL (0.32) | MGLL | |
| SCHEMBL726706 | 0.82 | MGLL (0.37) | TSHRMGLL | |
| SCHEMBL15991870 | 0.81 | MGLL (0.32) | MGLL | |
| SCHEMBL15991319 | 0.81 | MGLL (0.32) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160143937-A1 | METHODS OF USING CLEAVABLE DRUG CONJUGATES AND COMPOSITIONS THEREOF | Nguyen, Mark Quang (US) | 2016-05-26 | — | — | US | disclosed |
| US-9295731-B2 | Cleavable drug conjugates, compositions thereof and methods of use | Nguyen, Mark Quang (US) | 2016-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160143937-A1 | METHODS OF USING CLEAVABLE DRUG CONJUGATES AND COMPOSITIONS THEREOF | SI, PAICS, FURIN | TSHR 2893/4885MGLL 2521/4885GLA 332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.