Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11993176 | 0.88 | KDM4E (0.31) | MGLLALDH1A1KDM4EHPGDCYP2D6 | |
| SCHEMBL23631224 | 0.85 | MGLL (0.35) | MGLL | |
| SCHEMBL20445556 | 0.85 | MGLL (0.35) | MGLL | |
| SCHEMBL10455571 | 0.85 | MGLL (0.38) | MGLL | |
| SCHEMBL15800069 | 0.85 | MGLL (0.35) | MGLL | |
| SCHEMBL5140838 | 0.82 | MGLL (0.34) | MGLL | |
| SCHEMBL17635151 | 0.82 | TSHR (0.34) | MGLLTSHR | |
| SCHEMBL17635150 | 0.82 | TSHR (0.34) | MGLLTSHR | |
| SCHEMBL10126695 | 0.82 | MGLL (0.34) | MGLLKMT2AATM | |
| SCHEMBL208185 | 0.82 | MGLL (0.34) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240066133-A1 | THERAPEUTIC AGENTS AND CONJUGATES THEREOF | AJ SCIENCES (YIXING) CO., LTD (CN) | 2024-02-29 | — | — | US | disclosed |
| WO-2023005953-A1 | DRUG LOADING MONOMOLECULAR NANO POLYMER, PRODRUG, MICELLE, DRUG DELIVERY SYSTEM, PREPARATION METHOD, AND USE | 嘉兴清准医药科技有限公司 | 2023-02-02 | — | — | WO | disclosed |
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2022-05-10 | — | — | US | disclosed |
| US-10660969-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2020-05-26 | — | — | US | disclosed |
| US-20180214561-A1 | EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2018-08-02 | — | — | US | disclosed |
| WO-2018119449-A1 | OXAZEPINE DERIVATIVES HAVING TNAP INHIBITORY ACTIVITY | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-06-28 | — | — | WO | disclosed |
| US-9862682-B2 | Functionalized pegylated cyanine compounds, pharmaceutical compositions, and methods of use thereof | BroadPharm (US) | 2018-01-09 | — | — | US | disclosed |
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2017-11-02 | — | — | US | disclosed |
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2017-11-02 | — | — | US | disclosed |
| US-20170197916-A1 | FUNCTIONALIZED PEGYLATED CYANINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | BroadPharm (US) | 2017-07-13 | — | — | US | disclosed |
| US-20120214952-A1 | Methods for Preparing Polymeric Reagents and Compositions of Polymeric Reagents | NEKTAR THERAPEUTICS (US) | 2012-08-23 | — | — | US | disclosed |
| US-8193306-B2 | Methods for preparing polymeric reagents and compositions of polymeric reagents | NEKTAR THERAPEUTICS (US) | 2012-06-05 | — | — | US | disclosed |
| EP-2422780-A1 | Resistance-repellent retroviral protease inhibitors | Sequoia Pharmaceuticals, Inc. (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-2422781-A1 | Resistance-repellent retroviral protease inhibitors | Sequoia Pharmaceuticals, Inc. (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1664144-B1 | ACID-SENSITIVE POLYACETALS AND METHODS | NITTO DENKO CORP (JP) | 2011-04-27 | — | — | EP | disclosed |
| US-20110046000-A1 | METHODS TO INCREASE THE PHOTOSTABILITY OF DYES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-02-24 | — | — | US | disclosed |
| US-20100256310-A1 | Methods for Preparing Polymeric Reagents and Compositions of Polymeric Reagents | NEKTAR THERAPEUTICS (US) | 2010-10-07 | — | — | US | disclosed |
| US-7767784-B2 | Active carbonate esters of water-soluble polyoxyethylene glycol | NEKTAR THERAPEUTICS (US) | 2010-08-03 | — | — | US | disclosed |
| US-20080064851-A1 | Active carbonate esters of water-soluble polyoxyethylene glycol | NEKTAR THERAPEUTICS | 2008-03-13 | — | — | US | disclosed |
| WO-1994018229-A1 | 1,2,4-TRIAZINONE DERIVATIVES AND THEIR USE IN THERAPY | FISONS CORPORATION (US) | 1994-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10660969-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | MRPL38, ALG8, COG8 | MGLL 539/4885ALDH1A1 787/4885KDM4E 3210/4885 |
| US-20180214561-A1 | EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF | MRPL38, CXCL8, ALG8 | MGLL 1246/4885ALDH1A1 1061/4885KDM4E 2604/4885 |
| US-20170197916-A1 | FUNCTIONALIZED PEGYLATED CYANINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | ABL1, EGFR, ALB | MGLL 1481/4885ALDH1A1 1441/4885KDM4E 779/4885 |
| US-20110046000-A1 | METHODS TO INCREASE THE PHOTOSTABILITY OF DYES | PTMS, ACP1, SNRPE | MGLL 2822/4885ALDH1A1 3978/4885KDM4E 3420/4885 |
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | HDGF, F11, F12 | MGLL 1181/4885ALDH1A1 1582/4885KDM4E 4115/4885 |
| US-20240066133-A1 | THERAPEUTIC AGENTS AND CONJUGATES THEREOF | TLR9, STING1, TLR3 | MGLL 3991/4885ALDH1A1 4469/4885KDM4E 2007/4885 |
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | HDGF, F11, F12 | MGLL 1181/4885ALDH1A1 1582/4885KDM4E 4115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.