Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 7/20 | 0.80 |
| ▸ | SIRT3 | Q9NTG7 | 5/20 | 0.80 |
| ▸ | THRA | P10827 | 3/20 | 0.80 |
| ▸ | THRB | P10828 | 3/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.80 |
| ▸ | TP53 | P04637 | 2/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.80 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.80 |
| ▸ | KDM7A | Q6ZMT4 | 2/20 | 0.80 |
| ▸ | MLNR | O43193 | 1/20 | 0.80 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.80 |
| ▸ | PHF2 | O75151 | 1/20 | 0.80 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.80 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.80 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.80 |
| ▸ | FYN | P06241 | 1/20 | 0.80 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29879181 | 0.99 | ALDH1A1 (0.80) | KDM5ASIRT3THRATHRBALDH1A1 | |
| SCHEMBL15314978 | 0.90 | SIRT3 (0.70) | KDM5ASIRT3THRATHRBALDH1A1 | |
| SCHEMBL10679251 | 0.90 | SMPD1 (0.66) | KDM5ASIRT3THRATHRBALDH1A1 | |
| SCHEMBL15314959 | 0.89 | KDM5A (0.69) | KDM5ASIRT3THRATHRBALDH1A1 | |
| Amiodarone SCHEMBL29361787 | 0.89 | SIRT3 (1.00) | KDM5ASIRT3THRATHRBALDH1A1 | |
| Amiodarone SCHEMBL5496372 | 0.89 | SIRT3 (1.00) | KDM5ASIRT3THRATHRBALDH1A1 | |
| Amiodarone SCHEMBL12487240 | 0.89 | SIRT3 (1.00) | KDM5ASIRT3THRATHRBALDH1A1 | |
| Amiodarone SCHEMBL16284 | 0.89 | SIRT3 (1.00) | KDM5ASIRT3THRATHRBALDH1A1 | |
| Amiodarone SCHEMBL29362650 | 0.88 | ALDH1A1 (1.00) | KDM5ASIRT3THRATHRBALDH1A1 | |
| Amiodarone SCHEMBL28525007 | 0.88 | SIRT3 (0.98) | KDM5ASIRT3THRATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3001199-A1 | AUTOPHAGY AND PHOSPHOLIPIDOSIS PATHWAY ASSAYS | Enzo Life Sciences, Inc. (US) | 2016-03-30 | — | — | EP | disclosed |