Sugi Predict

Sugi Predict / Compounds / SCHEMBL176357

SCHEMBL176357

SCHEMBL176357

COc1ccc(C(=O)O)cc1[N+](=O)[O-]

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TTR P02766 1/20 0.68
▸ ALDH1A1 P00352 4/20 0.66
▸ TSHR P16473 3/20 0.66
▸ CYP3A4 P08684 1/20 0.66
▸ TDP1 Q9NUW8 1/20 0.66
▸ MAPT P10636 5/20 0.64
▸ KMT2A Q03164 3/20 0.64
▸ MEN1 O00255 2/20 0.64
▸ HPGD P15428 1/20 0.64
▸ CASP6 P55212 1/20 0.64
▸ SMN1; SMN2 Q16637 1/20 0.63
▸ CA12 O43570 1/20 0.61
▸ CA1 P00915 1/20 0.61
▸ CA2 P00918 1/20 0.61
▸ CA4 P22748 1/20 0.61
▸ CA6 P23280 1/20 0.61
▸ CA7 P43166 1/20 0.61
▸ TPMT P51580 1/20 0.61
▸ CA9 Q16790 1/20 0.61
▸ CA14 Q9ULX7 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9775617 0.98 TTR (0.67) TTRALDH1A1TSHRCYP3A4TDP1
SCHEMBL5740018 0.93 TTR (0.61) TTRALDH1A1TSHRCYP3A4TDP1
Benzoic Acid SCHEMBL27618286 0.89 ALDH1A1 (0.62) TTRALDH1A1TSHRCYP3A4TDP1
SCHEMBL2156946 0.88 ALDH1A1 (0.63) TTRALDH1A1TSHRCYP3A4TDP1
SCHEMBL3824914 0.88 ALDH1A1 (0.63) ALDH1A1TSHRCYP3A4TDP1MAPT
SCHEMBL7844171 0.87 ALDH1A1 (0.63) TTRALDH1A1TSHRCYP3A4TDP1
SCHEMBL29753668 0.87 TTR (0.64) TTRALDH1A1TSHRMAPTKMT2A
SCHEMBL30825381 0.87 ALDH1A1 (0.62) ALDH1A1TSHRCYP3A4TDP1MAPT
SCHEMBL4337680 0.87 ALDH1A1 (0.62) ALDH1A1TSHRCYP3A4TDP1MAPT
SCHEMBL223878 0.87 TTR (0.64) TTRALDH1A1TSHRMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 393 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 — — EP claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 — — WO claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 — — CN claimed
CN-114751841-A N- (3- (3-chlorobenzamide) phenyl) -4 methoxy-3-nitrobenzamide and preparation method and application thereof 重庆文理学院 2022-07-15 — — CN claimed
CN-111604021-B Oxidation reaction system for preparing red-based KD and control method thereof 舟山欧莱克新材料科技有限公司 2022-04-08 — — CN claimed
CN-110283475-B Preparation method of pigment red 146 杭州红妍颜料化工有限公司 2021-06-01 — — CN claimed
CN-111604021-A Oxidation reaction system for preparing red-based KD and control method thereof 舟山欧莱克新材料科技有限公司 2020-09-01 — — CN claimed
CN-110283475-A Preparation method of pigment red 146 杭州红妍颜料化工有限公司 2019-09-27 — — CN claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 — — US claimed
CN-104356000-B A kind of preparation method of 3-nitro-4-methoxybenzoic acid 响水恒利达科技化工有限公司 2016-09-28 — — CN claimed
WO-2010118241-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) 2010-10-14 — — WO claimed
US-7732625-B2 Colorant compounds XEROX CORPORATION (US) 2010-06-08 — — US claimed
US-7511000-B2 Gear part with lubrication coating and method of manufacturing the same NISSAN MOTOR CO., LTD. (JP) 2009-03-31 — — US claimed
US-7311767-B2 Forming a salt of a liquid phase change ink carrier of stearyl stearamide, an amine substituted Xanthene, acridine, anthracene or thioxanthene chromogen, and a metal salt capable of forming a compound with two chromogens XEROX CORPORATION (US) 2007-12-25 — — US claimed
US-7033424-B2 Phase change inks XEROX CORPORATION (US) 2006-04-25 — — US claimed
US-20060021546-A1 Processes for preparing phase change inks XEROX CORPORATION 2006-02-02 — — US claimed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 — — US claimed
US-20060016369-A1 PHASE CHANGE INKS XEROX CORPORATION 2006-01-26 — — US claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 — — US claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS TTR 347/4885ALDH1A1 3087/4885TSHR 1605/4885
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 TTR 2094/4885ALDH1A1 1569/4885TSHR 2894/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 TTR 22/4885ALDH1A1 1723/4885TSHR 4082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.