Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17636430 | 0.89 | TSHR (0.31) | LMNACHRNB2CHRNA4TSHRCYP3A4 | |
| SCHEMBL18220744 | 0.88 | — | — | |
| SCHEMBL8238473 | 0.79 | LMNA (0.34) | LMNAHSD17B10GAACHRNB2CHRNB4 | |
| SCHEMBL20052127 | 0.76 | CHRNB2 (0.37) | LMNAGAACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9102210 | 0.76 | LMNA (0.36) | LMNAHSD17B10CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL27537712 | 0.73 | BLM (0.34) | LMNAHSD17B10CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL27716789 | 0.70 | ACACB (0.34) | LMNAHSD17B10CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL19068425 | 0.70 | — | — | |
| SCHEMBL13126734 | 0.69 | CA1 (0.37) | CYP3A4TDP1 | |
| SCHEMBL29416854 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3000856-B1 | HOT MELT INKS | MARKEM IMAJE CORP (US) | 2020-04-22 | — | — | EP | disclosed |
| EP-3000852-B1 | NOVEL COMPOUNDS | MARKEM IMAJE CORP (US) | 2016-11-09 | — | — | EP | disclosed |
| EP-3000856-A1 | HOT MELT INKS | Markem-Imaje Corporation (US) | 2016-03-30 | — | — | EP | disclosed |
| EP-3000852-A1 | NOVEL COMPOUNDS | Markem-Imaje Corporation (US) | 2016-03-30 | — | — | EP | disclosed |