Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Emylcamate SCHEMBL387718 | 0.81 | ALOX15 (0.42) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL8238473 | 0.80 | LMNA (0.34) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL17636196 | 0.76 | LMNA (0.32) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL27891101 | 0.75 | MMP8 (0.35) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL27537712 | 0.74 | BLM (0.34) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL23786798 | 0.74 | ALOX15 (0.36) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL31412802 | 0.73 | GAA (0.41) | CYP3A4ALOX15CA1 | |
| SCHEMBL473499 | 0.73 | GAA (0.41) | CYP3A4ALOX15CA1 | |
| SCHEMBL27907896 | 0.73 | LMNA (0.52) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL23786745 | 0.72 | ALOX15 (0.34) | LMNAHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996036631-A1 | MULTIPLY-SUBSTITUTED FULLERENES AND METHODS FOR THEIR PREPARATION AND CHARACTERIZATION | SPHERE BIOSYSTEMS, INC. (US) | 1996-11-21 | — | — | WO | disclosed |