SCHEMBL17636588

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27933495	0.87	ESR2 (0.48)	ESR2ESR1LMNACYP1A2PGR
	SCHEMBL9066280	0.85	ESR2 (0.47)	ESR2ESR1LMNACYP1A2PGR
	SCHEMBL17636606	0.83	ESR1 (0.41)	ESR2ESR1SHBGLMNACYP1A2
	SCHEMBL344470	0.81	ESR2 (0.53)	ESR2ESR1CYP2D6OPRM1OPRD1
	SCHEMBL28309515	0.81	ESR2 (0.46)	ESR2ESR1SLC6A2SLC6A3OPRD1
	SCHEMBL17636585	0.80	ESR1 (0.58)	ESR2ESR1SHBGLMNAAR
	SCHEMBL21232543	0.80	ESR2 (0.41)	ESR2ESR1LMNACYP1A2PGR
	SCHEMBL7183973	0.79	ESR2 (0.55)	ESR2ESR1LMNACYP1A2CYP3A4
	SCHEMBL17636601	0.78	RORC (0.42)	ESR2ESR1SHBGALOX15
	SCHEMBL17636597	0.78	ACHE (0.53)	ESR2ESR1SHBGPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.