SCHEMBL17636601

SCHEMBL17636601

CCC(C)c1cc(C2(c3ccc(O)c(C(C)CC)c3)CCC(C(CC)C(CC)C3CCC(c4ccc(O)c(C(C)CC)c4)(c4ccc(O)c(C(C)CC)c4)CC3)CC2)ccc1O

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.42
TSHR P16473 1/20 0.38
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
USP2 O75604 1/20 0.34
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
PKM P14618 1/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34
SHBG P04278 2/20 0.33
THRA P10827 1/20 0.31
THRB P10828 1/20 0.31
PPARA Q07869 1/20 0.30
HDAC4 P56524 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17636606 0.86 ESR1 (0.41) ESR1ESR2USP2ALDH1A1GAA
SCHEMBL17636585 0.83 ESR1 (0.58) ESR1ESR2SHBGPPARA
SCHEMBL3297186 0.81 ESR1 (0.57) RORCTSHRESR1ESR2USP2
SCHEMBL29492954 0.81 ESR1 (0.57) RORCTSHRESR1ESR2USP2
SCHEMBL3019823 0.81 ESR1 (0.57) RORCTSHRESR1ESR2USP2
SCHEMBL29608284 0.81 ESR1 (0.57) RORCTSHRESR1ESR2USP2
SCHEMBL3816720 0.81 ESR2 (0.44) RORCTSHRESR1ESR2
SCHEMBL19620147 0.80 ALOX15 (0.38) ESR1ESR2ALDH1A1GAAALOX15
SCHEMBL17636588 0.78 ESR2 (0.48) ESR1ESR2ALOX15SHBG
SCHEMBL17636607 0.78 NUDT1 (0.42) ESR1ESR2SHBGTHRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9822237-B2 Resin composition, film, polarizing plate protective film, polarizing plate, liquid crystal display device, and bis type alicyclic cardo phenol compound FUJIFILM CORPORATION (JP) 2017-11-21 US disclosed
US-9822237-B2 Resin composition, film, polarizing plate protective film, polarizing plate, liquid crystal display device, and bis type alicyclic cardo phenol compound FUJIFILM CORPORATION (JP) 2017-11-21 US disclosed
US-20160090467-A1 RESIN COMPOSITION, FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE, AND BIS TYPE ALICYCLIC CARDO PHENOL COMPOUND FUJIFILM CORPORATION (JP) 2016-03-31 US disclosed
US-20160090467-A1 RESIN COMPOSITION, FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE, AND BIS TYPE ALICYCLIC CARDO PHENOL COMPOUND FUJIFILM CORPORATION (JP) 2016-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160090467-A1 RESIN COMPOSITION, FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE, AND BIS TYPE ALICYCLIC CARDO PHENOL COMPOUND RRS1, XIAP, ARID2 RORC 1069/4885TSHR 2454/4885ESR1 341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.