Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.56 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.55 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | TERT | O14746 | 3/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17661962 | 1.00 | LTA4H (0.56) | LTA4HSPHK1SPHK2S1PR1S1PR3 | |
| SCHEMBL13258710 | 0.95 | LTA4H (0.62) | LTA4HSPHK1SPHK2S1PR1S1PR3 | |
| SCHEMBL26266218 | 0.87 | SPHK1 (0.68) | SPHK1SPHK2S1PR1S1PR3S1PR4 | |
| SCHEMBL16847450 | 0.85 | SPHK1 (0.53) | LTA4HSPHK1SPHK2S1PR1S1PR3 | |
| SCHEMBL24668626 | 0.83 | LTA4H (0.54) | LTA4HSPHK1SPHK2S1PR1S1PR3 | |
| SCHEMBL14956872 | 0.83 | SPHK1 (0.52) | LTA4HSPHK1SPHK2S1PR1S1PR3 | |
| SCHEMBL17201789 | 0.83 | SPHK1 (0.52) | LTA4HSPHK1SPHK2S1PR1S1PR3 | |
| SCHEMBL20164120 | 0.83 | SPHK1 (0.52) | LTA4HSPHK1SPHK2S1PR1S1PR3 | |
| SCHEMBL12634418 | 0.83 | SPHK1 (0.51) | LTA4HSPHK1SPHK2S1PR1S1PR3 | |
| SCHEMBL17801791 | 0.83 | SPHK1 (0.51) | LTA4HSPHK1SPHK2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016046574-A1 | BIOLOGICAL MATERIALS AND USES THEREOF | ANTIKOR BIOPHARMA LIMITED (GB) | 2016-03-31 | — | — | WO | disclosed |