SCHEMBL17640480

SCHEMBL17640480

c1ccc(-c2ccc3oc4c(-c5ccc6c7ccccc7c7ccccc7c6c5)nccc4c3c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.41
PLA2G4A P47712 3/20 0.41
TDO2 P48775 4/20 0.38
HTR2B P41595 2/20 0.38
HTR5A P47898 2/20 0.38
MAPT P10636 2/20 0.37
MEN1 O00255 1/20 0.37
CSF1R P07333 1/20 0.37
PDGFRB P09619 1/20 0.37
KIT P10721 1/20 0.37
FLT3 P36888 1/20 0.37
KMT2A Q03164 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
PIM1 P11309 1/20 0.37
CSNK2A2 P19784 1/20 0.37
CSNK2B P67870 1/20 0.37
PIM3 Q86V86 1/20 0.37
PIM2 Q9P1W9 1/20 0.37
PLA2G10 O15496 1/20 0.36
PRKDC P78527 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17640474 0.96 MAPT (0.40) PLA2G2APLA2G4ATDO2HTR2BHTR5A
SCHEMBL11941231 0.84 MAPT (0.38) PLA2G2APLA2G4ATDO2HTR2BHTR5A
SCHEMBL25052666 0.84 PLA2G2A (0.50) PLA2G2APLA2G4AMAPTMEN1CSF1R
SCHEMBL25052951 0.84 PLA2G2A (0.50) PLA2G2APLA2G4AMAPTMEN1CSF1R
SCHEMBL25052348 0.84 PLA2G2A (0.50) PLA2G2APLA2G4AMAPTMEN1CSF1R
SCHEMBL11941230 0.83 MAPT (0.39) PLA2G2APLA2G4ATDO2HTR2BHTR5A
SCHEMBL22698477 0.83 PIM1 (0.38) PLA2G2APLA2G4ATDO2HTR2BHTR5A
SCHEMBL17640477 0.82 KDM4E (0.32) TDO2MAPTNPC1L3MBTL1KDM4E
SCHEMBL16582802 0.81 ALOX5 (0.42) PLA2G2APLA2G4ATDO2MAPTMEN1
SCHEMBL25052369 0.81 PLA2G2A (0.49) PLA2G2APLA2G4AMAPTMEN1CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160093808-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-03-31 US disclosed