Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 7/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16141240 | 0.93 | ALOX5 (0.53) | ALOX5MAPTMEN1KMT2ACSF1R | |
| SCHEMBL16922466 | 0.91 | ALDH1A1 (0.40) | ALOX5MAPTMEN1KMT2ACSF1R | |
| SCHEMBL16922470 | 0.89 | ALDH1A1 (0.40) | ALOX5MAPTMEN1KMT2ACSF1R | |
| SCHEMBL24796192 | 0.89 | MAPT (0.51) | ALOX5MAPTMEN1KMT2ACSF1R | |
| SCHEMBL17701406 | 0.88 | PLA2G2A (0.39) | ALOX5MAPTMEN1KMT2ACSF1R | |
| SCHEMBL16141245 | 0.86 | KDM4E (0.36) | ALOX5MAPTMEN1KMT2ACSF1R | |
| SCHEMBL16922467 | 0.86 | MAPT (0.39) | ALOX5MAPTMEN1KMT2ACSF1R | |
| SCHEMBL24263767 | 0.85 | MAPT (0.46) | ALOX5MAPTMEN1KMT2ACSF1R | |
| SCHEMBL16141244 | 0.83 | ALOX5 (0.44) | ALOX5MAPTNPC1TDO2GGPS1 | |
| SCHEMBL11941230 | 0.83 | MAPT (0.39) | ALOX5MAPTMEN1KMT2ACSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3044286-B1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2018-01-31 | — | — | EP | disclosed |
| US-20160226001-A1 | Organic Electroluminescent Device | MERCK PATENT GMBH (DE) | 2016-08-04 | — | — | US | disclosed |
| US-20160226001-A1 | Organic Electroluminescent Device | MERCK PATENT GMBH (DE) | 2016-08-04 | — | — | US | disclosed |
| WO-2015036080-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2015-03-19 | — | — | WO | disclosed |