Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25580282 | 0.88 | CYP3A4 (0.50) | CYP3A4CYP1A2CYP2C19LMNAHSD17B10 | |
| SCHEMBL13047834 | 0.85 | CYP3A4 (0.59) | CYP3A4CYP1A2CYP2C19LMNAHSD17B10 | |
| SCHEMBL17629282 | 0.84 | PAX8 (0.44) | CYP3A4CYP1A2CYP2C19LMNAHSD17B10 | |
| SCHEMBL6505435 | 0.79 | CYP3A4 (0.57) | CYP3A4CYP1A2CYP2C19LMNAKDM4E | |
| SCHEMBL6431720 | 0.75 | L3MBTL1 (0.56) | CYP3A4CYP1A2CYP2C19LMNAKDM4E | |
| SCHEMBL3743002 | 0.74 | KDM4E (0.48) | CYP3A4CYP1A2CYP2C19LMNAHSD17B10 | |
| SCHEMBL13047402 | 0.74 | HSD17B10 (0.50) | CYP3A4CYP1A2CYP2C19LMNAHSD17B10 | |
| SCHEMBL13602416 | 0.73 | KDM4E (0.58) | CYP3A4CYP1A2CYP2C19LMNAHSD17B10 | |
| SCHEMBL17629283 | 0.73 | PAX8 (0.43) | CYP3A4CYP1A2CYP2C19LMNAHSD17B10 | |
| SCHEMBL11390772 | 0.73 | CYP1A2 (0.56) | CYP3A4CYP1A2CYP2C19LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016046078-A1 | HERBICIDAL PYRIDINO-/PYRIMIDINO-THIAZOLES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-31 | — | — | WO | disclosed |