SCHEMBL17629282

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17629283	0.89	PAX8 (0.43)	PAX8CDC7DBF4CYP1A2CYP3A4
	SCHEMBL13074934	0.87	PAX8 (0.46)	PAX8CDC7DBF4CYP1A2CYP3A4
	SCHEMBL15047295	0.87	CYP1A2 (0.52)	PAX8CDC7DBF4CYP1A2CYP3A4
	SCHEMBL17629288	0.87	PAX8 (0.46)	PAX8CDC7DBF4CYP1A2CYP3A4
	SCHEMBL290820	0.86	PAX8 (0.45)	PAX8CDC7DBF4CYP1A2CYP3A4
	SCHEMBL17629289	0.86	PAX8 (0.45)	PAX8CDC7DBF4CYP1A2CYP3A4
	SCHEMBL290378	0.86	PAX8 (0.45)	PAX8CDC7DBF4CYP1A2CYP3A4
	SCHEMBL17641122	0.84	CYP3A4 (0.47)	CDC7DBF4CYP1A2CYP3A4LMNA
	SCHEMBL13047246	0.84	PAX8 (0.43)	PAX8CDC7DBF4CYP1A2CYP3A4
	SCHEMBL290269	0.84	PAX8 (0.43)	PAX8CDC7DBF4CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.