Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | HINT1 | P49773 | 2/20 | 0.30 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17000749 | 0.87 | KDM4E (0.42) | KDM4ETAS1R3TAS1R1ALDH1A1MEN1 | |
| SCHEMBL18045591 | 0.86 | KDM4E (0.41) | KDM4ETAS1R3TAS1R1ALDH1A1MEN1 | |
| SCHEMBL21166690 | 0.86 | KDM4E (0.41) | KDM4ETAS1R3TAS1R1ALDH1A1MEN1 | |
| SCHEMBL18513340 | 0.83 | KDM4E (0.40) | KDM4ETAS1R3TAS1R1ALDH1A1MEN1 | |
| SCHEMBL17641398 | 0.80 | AHCY (0.49) | — | |
| SCHEMBL18513298 | 0.78 | KDM4E (0.45) | KDM4ETAS1R3TAS1R1ALDH1A1MEN1 | |
| SCHEMBL17641479 | 0.77 | HINT1 (0.46) | HINT1 | |
| SCHEMBL29546511 | 0.77 | KDM4E (0.43) | KDM4ETAS1R3TAS1R1ALDH1A1MEN1 | |
| SCHEMBL29546557 | 0.76 | KDM4E (0.40) | KDM4ETAS1R3TAS1R1ALDH1A1MEN1 | |
| SCHEMBL18513423 | 0.76 | KDM4E (0.41) | KDM4ETAS1R3TAS1R1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016049415-A1 | 4'-VINYL SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS RNA REPLICATION | RIBOSCIENCE LLC (US) | 2016-03-31 | — | — | WO | disclosed |