Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | HINT1 | P49773 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29546511 | 0.93 | KDM4E (0.43) | KDM4EMEN1KMT2ATSHRTAS1R3 | |
| SCHEMBL27174759 | 0.91 | MEN1 (0.41) | KDM4EMEN1KMT2ATSHRTAS1R3 | |
| SCHEMBL29546506 | 0.89 | MEN1 (0.40) | KDM4EMEN1KMT2ATSHRTAS1R3 | |
| SCHEMBL2157716 | 0.83 | KDM4E (0.41) | KDM4EMEN1KMT2ATSHRTAS1R3 | |
| SCHEMBL29546595 | 0.81 | TAS1R3 (0.47) | KDM4EMEN1KMT2ATSHRTAS1R3 | |
| SCHEMBL29546748 | 0.81 | KDM4E (0.38) | KDM4EMEN1KMT2ATSHRTAS1R3 | |
| SCHEMBL17000749 | 0.77 | KDM4E (0.42) | KDM4EMEN1KMT2ATSHRTAS1R3 | |
| SCHEMBL25401406 | 0.76 | KDM4E (0.41) | KDM4EMEN1KMT2ATSHRTAS1R3 | |
| SCHEMBL25401401 | 0.76 | KDM4E (0.41) | KDM4EMEN1KMT2ATSHRTAS1R3 | |
| SCHEMBL17641433 | 0.76 | KDM4E (0.41) | KDM4EMEN1KMT2ATSHRTAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232455-A2 | NOVEL LIGANDS FOR ASIALOGLYCOPROTEIN RECEPTOR | Sanofi (FR) | 2023-08-30 | — | — | EP | disclosed |
| CN-116368146-A | Novel ligands for asialoglycoprotein receptors | 赛诺菲 | 2023-06-30 | — | — | CN | disclosed |
| WO-2022084331-A2 | NOVEL LIGANDS FOR ASIALOGLYCOPROTEIN RECEPTOR | SANOFI (FR) | 2022-04-28 | — | — | WO | disclosed |