Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 5/20 | 0.51 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17641398 | 0.88 | AHCY (0.49) | AHCYEHMT1HSP90B1 | |
| SCHEMBL12429685 | 0.86 | AHCY (0.44) | AHCYEHMT1PRMT5WDR77 | |
| SCHEMBL19221815 | 0.85 | AHCY (0.52) | AHCYEHMT1PRMT5WDR77HSP90B1 | |
| SCHEMBL17000652 | 0.84 | AHCY (0.51) | AHCYEHMT1PRMT5WDR77HSP90B1 | |
| SCHEMBL17641479 | 0.83 | HINT1 (0.46) | — | |
| SCHEMBL17633015 | 0.81 | AHCY (0.54) | AHCYPRMT5WDR77 | |
| SCHEMBL17446882 | 0.80 | AHCY (0.52) | AHCYEHMT1PRMT5WDR77HSP90B1 | |
| SCHEMBL12386685 | 0.79 | PRMT5 (0.56) | AHCYEHMT1PRMT5WDR77HSP90B1 | |
| SCHEMBL18073288 | 0.79 | PRMT5 (0.56) | AHCYEHMT1PRMT5WDR77HSP90B1 | |
| SCHEMBL15267255 | 0.77 | AHCY (0.51) | AHCYEHMT1HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264611-A1 | 4'-VINYL SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS RNA REPLICATION | RIBOSCIENCE LLC | 2016-09-15 | — | — | US | disclosed |
| WO-2016049415-A1 | 4'-VINYL SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS RNA REPLICATION | RIBOSCIENCE LLC (US) | 2016-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264611-A1 | 4'-VINYL SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS RNA REPLICATION | NSUN2, RNMT, RRM2 | AHCY 2316/4885EHMT1 1720/4885PRMT5 366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.