Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PI4KA | P42356 | 4/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954470 | 0.89 | HCAR1 (0.46) | ATMMEN1KMT2AHCAR1ALDH1A1 | |
| SCHEMBL10288659 | 0.87 | POLB (0.53) | ATMMEN1KMT2AHCAR1MAPT | |
| SCHEMBL9954589 | 0.87 | ALOX12 (0.50) | ATMMEN1KMT2AALDH1A1RXFP1 | |
| SCHEMBL10289024 | 0.85 | SMN1; SMN2 (0.55) | MEN1KMT2AALDH1A1MAPTPI4KA | |
| SCHEMBL9954343 | 0.84 | MAPT (0.49) | ATMMEN1KMT2AHCAR1ALDH1A1 | |
| SCHEMBL9954958 | 0.82 | ALDH1A1 (0.47) | ATMMEN1KMT2AALDH1A1GABRA1 | |
| SCHEMBL9953324 | 0.82 | HCAR1 (0.50) | HCAR1PI4KAPIK3CGKDM4E | |
| SCHEMBL9670140 | 0.82 | MEN1 (0.51) | ATMMEN1KMT2AALDH1A1RXFP1 | |
| SCHEMBL9954421 | 0.82 | MEN1 (0.51) | ATMMEN1KMT2AHCAR1ALDH1A1 | |
| SCHEMBL9954094 | 0.82 | HCAR1 (0.51) | ATMHCAR1MAPTPI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |