Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.46 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | CCR1 | P32246 | 2/20 | 0.44 |
| ▸ | CCR5 | P51681 | 2/20 | 0.44 |
| ▸ | CCR8 | P51685 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9358988 | 0.79 | MCL1 (0.59) | MAPTKDM4ETET2TET1LMNA | |
| SCHEMBL17643170 | 0.77 | NCOA1 (0.49) | MAPTKDM4ELMNACYP3A4HSP90AA1 | |
| SCHEMBL2098564 | 0.76 | MCL1 (0.67) | MAPTKDM4EHTTSMN1; SMN2TDP1 | |
| SCHEMBL11995709 | 0.74 | PARP1 (0.55) | MAPTKDM4ETET2TET1LMNA | |
| SCHEMBL7315090 | 0.73 | LMNA (0.48) | MAPTKDM4ELMNACCR1CCR5 | |
| SCHEMBL5447698 | 0.73 | MAPT (0.54) | MAPTKDM4ETET2TET1LMNA | |
| SCHEMBL31300928 | 0.72 | TET2 (0.55) | MAPTKDM4ETET2TET1LMNA | |
| SCHEMBL963923 | 0.72 | TET2 (0.55) | MAPTKDM4ETET2TET1LMNA | |
| SCHEMBL14347292 | 0.72 | MAPT (0.56) | MAPTKDM4ETET2TET1LMNA | |
| SCHEMBL5453249 | 0.72 | MAPT (0.52) | MAPTKDM4ETET2TET1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197982-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-05-06 | — | — | EP | disclosed |
| US-10544360-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2020-01-28 | — | — | US | disclosed |
| WO-2016045765-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-03-31 | — | — | WO | disclosed |