SCHEMBL5447698

SCHEMBL5447698

O=c1[nH]c2c(ccc3cccnc32)c(Br)c1Br.[Cu]

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.54
KDM4E B2RXH2 2/20 0.54
TET2 Q6N021 1/20 0.46
TET1 Q8NFU7 1/20 0.46
LMNA P02545 5/20 0.44
TP53 P04637 4/20 0.44
CCR1 P32246 2/20 0.44
CCR5 P51681 2/20 0.44
CCR8 P51685 2/20 0.44
CYP3A4 P08684 2/20 0.44
GMNN O75496 1/20 0.44
HSP90AA1 P07900 1/20 0.44
MMP2 P08253 1/20 0.44
CYP2D6 P10635 1/20 0.44
MMP9 P14780 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
NFKB1 P19838 1/20 0.44
MMP8 P22894 1/20 0.44
THPO P40225 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5453249 0.81 MAPT (0.52) MAPTKDM4ETET2TET1LMNA
SCHEMBL11995709 0.80 PARP1 (0.55) MAPTKDM4ETET2TET1LMNA
SCHEMBL17643178 0.73 MAPT (0.54) MAPTKDM4ETET2TET1LMNA
SCHEMBL14374170 0.72 MAPT (0.56) MAPTKDM4ETET2TET1LMNA
SCHEMBL14347292 0.72 MAPT (0.56) MAPTKDM4ETET2TET1LMNA
SCHEMBL22761944 0.71 MAPT (0.59) MAPTKDM4ETET2TET1LMNA
SCHEMBL22762124 0.71 KDM4E (0.59) MAPTKDM4ETET2TET1LMNA
SCHEMBL29871779 0.70 MAPT (0.54) MAPTKDM4ETET2TET1LMNA
SCHEMBL6847092 0.70 MAPT (0.54) MAPTKDM4ETET2TET1LMNA
SCHEMBL8128555 0.70 KIF11 (0.61) MAPTKDM4ELMNATP53CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070184366-A1 DYE CONTAINING CURABLE COMPOSITION, COLOR FILTER, AND PROCESS OF PREPARING COLOR FILTER FUJIFILM CORPORATION 2007-08-09 US disclosed
US-20070099096-A1 Dye-containing curable composition, color filter and method of producing thereof FUJIFILM CORPORATION 2007-05-03 US disclosed