Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTUD7B | Q6GQQ9 | 5/20 | 0.54 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.51 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.45 |
| ▸ | ACP1 | P24666 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632124 | 0.83 | OTUD7B (0.76) | OTUD7BUSP30MKNK1UCHL1 | |
| SCHEMBL25052368 | 0.83 | OTUD7B (0.76) | OTUD7BUSP30MKNK1UCHL1 | |
| SCHEMBL17643987 | 0.72 | OTUD7B (0.53) | OTUD7BUSP30NPY5R | |
| SCHEMBL2900888 | 0.71 | KDR (0.55) | OTUD7BUSP30MKNK1GSTO1KDR | |
| SCHEMBL19049845 | 0.70 | OTUD7B (1.00) | OTUD7BUSP30UCHL1 | |
| SCHEMBL19031337 | 0.70 | OTUD7B (1.00) | OTUD7BUSP30UCHL1 | |
| SCHEMBL17643981 | 0.70 | OTUD7B (0.75) | OTUD7BUSP30KDRUCHL1 | |
| SCHEMBL17632243 | 0.70 | OTUD7B (0.68) | OTUD7BUSP30MKNK1UCHL1 | |
| SCHEMBL25052373 | 0.70 | OTUD7B (0.68) | OTUD7BUSP30MKNK1UCHL1 | |
| SCHEMBL19281681 | 0.70 | OTUD7B (0.71) | OTUD7BUSP30MKNK1UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |