SCHEMBL25052368

SCHEMBL25052368

C[C@]1(C(=O)Nc2ncc(-c3ccccc3)s2)CCN(C#N)C1

nearest known ligand 0.76

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ OTUD7B Q6GQQ9 9/20 0.76
▸ USP30 Q70CQ3 9/20 0.71
▸ UCHL1 P09936 1/20 0.59
▸ MKNK1 Q9BUB5 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17632124 1.00 OTUD7B (0.76) OTUD7BUSP30UCHL1MKNK1
SCHEMBL19049845 0.87 OTUD7B (1.00) OTUD7BUSP30UCHL1
SCHEMBL19031337 0.87 OTUD7B (1.00) OTUD7BUSP30UCHL1
SCHEMBL17643981 0.87 OTUD7B (0.75) OTUD7BUSP30UCHL1
SCHEMBL19281681 0.86 OTUD7B (0.71) OTUD7BUSP30UCHL1MKNK1
SCHEMBL17632243 0.86 OTUD7B (0.68) OTUD7BUSP30UCHL1MKNK1
SCHEMBL25052373 0.86 OTUD7B (0.68) OTUD7BUSP30UCHL1MKNK1
SCHEMBL17643723 0.83 OTUD7B (0.54) OTUD7BUSP30UCHL1MKNK1
SCHEMBL23198240 0.83 USP30 (1.00) OTUD7BUSP30UCHL1
SCHEMBL23403452 0.82 OTUD7B (0.54) OTUD7BUSP30UCHL1MKNK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230052191-A1 NOVEL COMPOUNDS MISSION THERAPEUTICS LTD (GB) 2023-02-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230052191-A1 NOVEL COMPOUNDS UCHL1, UCHL3, UCHL5 OTUD7B 64/4885USP30 19/4885UCHL1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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