SCHEMBL17632243

SCHEMBL17632243

COCC1(C(=O)Nc2ncc(-c3ccccc3)s2)CCN(C#N)C1

nearest known ligand 0.68

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ OTUD7B Q6GQQ9 8/20 0.68
▸ USP30 Q70CQ3 10/20 0.63
▸ UCHL1 P09936 1/20 0.53
▸ MKNK1 Q9BUB5 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25052373 1.00 OTUD7B (0.68) OTUD7BUSP30UCHL1MKNK1
SCHEMBL17632028 0.94 OTUD7B (0.61) OTUD7BUSP30UCHL1MKNK1
SCHEMBL17632124 0.86 OTUD7B (0.76) OTUD7BUSP30UCHL1MKNK1
SCHEMBL25052368 0.86 OTUD7B (0.76) OTUD7BUSP30UCHL1MKNK1
SCHEMBL19281681 0.84 OTUD7B (0.71) OTUD7BUSP30UCHL1MKNK1
SCHEMBL17632460 0.83 OTUD7B (0.49) OTUD7BUSP30UCHL1
SCHEMBL17632480 0.82 OTUD7B (0.47) OTUD7BUSP30MKNK1
SCHEMBL19049845 0.81 OTUD7B (1.00) OTUD7BUSP30UCHL1
SCHEMBL19031337 0.81 OTUD7B (1.00) OTUD7BUSP30UCHL1
SCHEMBL17643981 0.81 OTUD7B (0.75) OTUD7BUSP30UCHL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828179-A1 CYANOPYRROLIDINES AS DUB MODULATORS Mission Therapeutics Limited (GB) 2021-06-02 — — EP claimed
EP-3197883-B1 NOVEL COMPOUNDS MISSION THERAPEUTICS LTD (GB) 2020-03-18 — — EP claimed
CN-107001339-B Novel compounds 特殊治疗有限公司 2020-03-17 — — CN claimed
US-10392380-B2 Compounds MISSION THERAPEUTICS LIMITED (GB) 2019-08-27 — — US claimed
US-20180162852-A1 NOVEL COMPOUNDS MISSION THERAPEUTICS LIMITED 2018-06-14 — — US claimed
US-9926307-B2 Compounds MISSION THERAPEUTICS LTD (GB) 2018-03-27 — — US claimed
US-20170247365-A1 NOVEL COMPOUNDS MISSION THERAPEUTICS LTD (GB) 2017-08-31 — — US claimed
US-11993595-B2 Compounds MISSION THERAPEUTICS LIMITED (GB) 2024-05-28 — — US disclosed
CN-111592534-B New compounds 特殊治疗有限公司 2023-06-30 — — CN disclosed
US-20230052191-A1 NOVEL COMPOUNDS MISSION THERAPEUTICS LTD (GB) 2023-02-16 — — US disclosed
US-11472798-B2 Compounds MISSION THERAPEUTICS LTD (GB) 2022-10-18 — — US disclosed
EP-3828179-A1 CYANOPYRROLIDINES AS DUB MODULATORS Mission Therapeutics Limited (GB) 2021-06-02 — — EP disclosed
EP-3828179-A1 CYANOPYRROLIDINES AS DUB MODULATORS Mission Therapeutics Limited (GB) 2021-06-02 — — EP disclosed
US-9926307-B2 Compounds MISSION THERAPEUTICS LTD (GB) 2018-03-27 — — US disclosed
US-9926307-B2 Compounds MISSION THERAPEUTICS LTD (GB) 2018-03-27 — — US disclosed
US-20170247365-A1 NOVEL COMPOUNDS MISSION THERAPEUTICS LTD (GB) 2017-08-31 — — US disclosed
US-20170247365-A1 NOVEL COMPOUNDS MISSION THERAPEUTICS LTD (GB) 2017-08-31 — — US disclosed
US-20170247365-A1 NOVEL COMPOUNDS MISSION THERAPEUTICS LTD (GB) 2017-08-31 — — US disclosed
EP-3197883-A1 NOVEL COMPOUNDS Mission Therapeutics Limited (GB) 2017-08-02 — — EP disclosed
WO-2016046530-A1 NOVEL COMPOUNDS MISSION THERAPEUTICS LTD (GB) 2016-03-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11472798-B2 Compounds UCHL1, UCHL3, UCHL5 OTUD7B 57/4885USP30 20/4885UCHL1 1/4885
US-20180162852-A1 NOVEL COMPOUNDS UCHL1, UCHL3, UCHL5 OTUD7B 64/4885USP30 19/4885UCHL1 1/4885
US-10392380-B2 Compounds UCHL1, UCHL3, UCHL5 OTUD7B 57/4885USP30 20/4885UCHL1 1/4885
US-11993595-B2 Compounds UCHL1, UCHL3, UCHL5 OTUD7B 57/4885USP30 20/4885UCHL1 1/4885
US-20170247365-A1 NOVEL COMPOUNDS UCHL1, UCHL3, UCHL5 OTUD7B 64/4885USP30 19/4885UCHL1 1/4885
US-20230052191-A1 NOVEL COMPOUNDS UCHL1, UCHL3, UCHL5 OTUD7B 64/4885USP30 19/4885UCHL1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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