SCHEMBL1764699

SCHEMBL1764699

CC(C)(C)OC(=O)C1CCCC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.49
BTK Q06187 1/20 0.44
ADRB2 P07550 1/20 0.42
ADRB1 P08588 1/20 0.42
ADRB3 P13945 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
HSD17B10 Q99714 1/20 0.41
HPGD P15428 1/20 0.41
ATM Q13315 1/20 0.40
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
GAA P10253 1/20 0.40
KMT2A Q03164 2/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
EPHX1 P07099 2/20 0.39
MAPK1 P28482 1/20 0.38
ALDH1A1 P00352 2/20 0.37
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27793145 0.98 HRH3 (0.47) HRH3BTKADRB2ADRB1ADRB3
SCHEMBL31356450 0.98 HRH3 (0.47) HRH3BTKADRB2ADRB1ADRB3
SCHEMBL28655866 0.98 HRH3 (0.47) HRH3BTKADRB2ADRB1ADRB3
SCHEMBL11752523 0.98 HRH3 (0.47) HRH3BTKADRB2ADRB1ADRB3
SCHEMBL28172293 0.98 HRH3 (0.47) HRH3BTKADRB2ADRB1ADRB3
SCHEMBL1409272 0.98 HRH3 (0.47) HRH3BTKADRB2ADRB1ADRB3
SCHEMBL1690233 0.95 HRH3 (0.49) HRH3BTKADRB2ADRB1ADRB3
SCHEMBL186721 0.90 HRH3 (0.51) HRH3BTKSMN1; SMN2HSD17B10HPGD
SCHEMBL1295721 0.90 HRH3 (0.51) HRH3BTKSMN1; SMN2HSD17B10HPGD
SCHEMBL28492122 0.90 HRH3 (0.51) HRH3BTKSMN1; SMN2HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019055985-A1 CLICK CHEMISTRY APTAMER TAGGING FOR EAB BIOSENSORS ECCRINE SYSTEMS, INC. (US) 2019-03-21 WO claimed
US-12037337-B2 Compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2024-07-16 US disclosed
US-20240237518-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-07-11 US disclosed
US-20240218115-A1 BRANCHED POLY(3-HYDROXYPROPIONIC ACID)POLYMER, AND METHOD FOR PREPARATION THEREOF LG CHEM, LTD. (KR) 2024-07-04 US disclosed
US-20240215441-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-06-27 US disclosed
US-20240208991-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD (KR) 2024-06-27 US disclosed
US-12022730-B2 Compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2024-06-25 US disclosed
CN-115010597-B Synthesis method of cyclopentanecarboxylic acid 湖北玖天生物医药科技有限公司 2024-06-07 CN disclosed
US-20240025840-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2024-01-25 US disclosed
US-20240023355-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-01-18 US disclosed
EP-0767794-B1 PHOSPHINIC ACID DERIVATIVES SCHERING CORP (US) 2000-02-02 EP disclosed
EP-0933993-A1 SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS BIOCRYST PHARMACEUTICALS INC. (US) 1999-08-11 EP disclosed
CN-1222509-A New pyrrole compounds, process for their preparation and pharmaceutical compositions containing them ADIR (FR) 1999-07-14 CN disclosed
WO-1997047194-A1 SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS BIOCRYST PHARMACEUTICALS, INC. (US) 1997-12-18 WO disclosed
EP-0767794-A1 PHOSPHINIC ACID DERIVATIVES SCHERING CORPORATION (US) 1997-04-16 EP disclosed
WO-1996000732-A9 PHOSPHINIC ACID DERIVATIVES 1996-02-22 WO disclosed
WO-1996000732-A1 PHOSPHINIC ACID DERIVATIVES SCHERING CORPORATION (US) 1996-01-11 WO disclosed
US-5476847-A Treating cardiovascular, gastrointestinal, urogenital disorders SCHERING CORPORATION (US) 1995-12-19 US disclosed
US-5407960-A For cardiovascualr disorders, pain SCHERING CORPORATION (US) 1995-04-18 US disclosed
WO-1991009840-A1 MERCAPTOCYCLOACYL AMINOACID ENDOPEPTIDASE INHIBITORS SCHERING CORPORATION (US) 1991-07-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240023355-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CRY2, CYP1A1 HRH3 4489/4885BTK 1539/4885ADRB2 780/4885
US-20240208991-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CRY1, CCNL2, UBE2L3 HRH3 624/4885BTK 1676/4885ADRB2 1163/4885
US-12037337-B2 Compound and organic light emitting device comprising the same CRY1, CRY2, C1S HRH3 183/4885BTK 3119/4885ADRB2 298/4885
US-20240215441-A1 ORGANIC LIGHT EMITTING DEVICE CRY2, CRY1, AHR HRH3 610/4885BTK 3144/4885ADRB2 72/4885
US-12022730-B2 Compound and organic light emitting device comprising the same CRY1, ARRB1, CYP1A1 HRH3 216/4885BTK 4011/4885ADRB2 452/4885
US-20240025840-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CRY1, CYP1A1, TMEM109 HRH3 3233/4885BTK 2168/4885ADRB2 2164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.