Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506661 | 0.84 | HDAC1 (0.48) | MEN1KMT2AMAPTALOX5 | |
| SCHEMBL11184042 | 0.82 | TSHR (0.53) | TSHRAKT1ALDH1A1MAPK1TDP1 | |
| SCHEMBL176484 | 0.82 | TSHR (0.53) | TSHRAKT1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9542297 | 0.81 | TSHR (0.49) | TSHRAKT1ALDH1A1MAPK1TDP1 | |
| SCHEMBL8588107 | 0.81 | TSHR (0.51) | TSHRAKT1ALDH1A1MAPK1TDP1 | |
| SCHEMBL9474105 | 0.80 | TSHR (0.48) | TSHRAKT1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL4553820 | 0.79 | TSHR (0.50) | TSHRAKT1ALDH1A1MAPK1TDP1 | |
| SCHEMBL8719506 | 0.79 | TSHR (0.50) | TSHRAKT1ALDH1A1MAPK1TDP1 | |
| SCHEMBL11684728 | 0.79 | TSHR (0.50) | TSHRAKT1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9541184 | 0.79 | TSHR (0.54) | TSHRAKT1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |
| US-4008192-A | Polyisocyanates blocked with hydroxamic acid esters or acyl hydroxamates | AKZO N.V. (NL) | 1977-02-15 | — | — | US | disclosed |