Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1764927 | 1.00 | TAAR1 (0.55) | TAAR1SIGMAR1SLC18A2OPRD1OPRK1 | |
| SCHEMBL1697045 | 0.87 | SIGMAR1 (0.64) | TAAR1SIGMAR1SLC18A2OPRM1CYP2D6 | |
| SCHEMBL172645 | 0.81 | SLC6A4 (0.61) | TAAR1SIGMAR1SLC18A2SLC6A4EPHX1 | |
| SCHEMBL12289294 | 0.81 | SLC6A4 (0.61) | TAAR1SIGMAR1SLC18A2SLC6A4EPHX1 | |
| SCHEMBL9341390 | 0.81 | SLC6A4 (0.61) | TAAR1SIGMAR1SLC18A2SLC6A4EPHX1 | |
| SCHEMBL22364527 | 0.80 | SLC6A2 (0.54) | TAAR1SIGMAR1SLC18A2OPRD1OPRK1 | |
| SCHEMBL23157064 | 0.80 | EPHX1 (0.58) | TAAR1SIGMAR1SLC18A2OPRD1OPRK1 | |
| SCHEMBL2629129 | 0.79 | SIGMAR1 (0.55) | TAAR1SIGMAR1SLC18A2OPRM1SLC6A2 | |
| SCHEMBL21550512 | 0.79 | TAAR1 (0.55) | TAAR1SIGMAR1SLC18A2OPRD1OPRK1 | |
| SCHEMBL10062064 | 0.79 | SIGMAR1 (0.55) | TAAR1SIGMAR1SLC18A2OPRM1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1390340-B1 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INST TECHNOLOGY (US) | 2017-03-01 | — | — | EP | disclosed |
| EP-2504324-B1 | SULTAM DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2015-02-25 | — | — | EP | disclosed |
| US-8314250-B2 | Sultam derivatives | HOFFMANN-LA ROCHE INC. (US) | 2012-11-20 | — | — | US | disclosed |
| EP-2504324-A1 | SULTAM DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2012-10-03 | — | — | EP | disclosed |
| WO-2011064141-A1 | SULTAM DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-06-03 | — | — | WO | disclosed |
| US-20110124686-A1 | SULTAM DERIVATIVES | ANDERSON KEVIN W | 2011-05-26 | — | — | US | disclosed |
| US-4704464-A | CHELATE COMPOUNDS | ASTA-WERKE AKTIENGESELLSCHAFT CHEMISCHE FABRIK (DE) | 1987-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124686-A1 | SULTAM DERIVATIVES | SULT1A1, SULT2A1, SULT1E1 | TAAR1 2713/4885SIGMAR1 535/4885SLC18A2 1999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.