Sugi Predict

Sugi Predict / Compounds / SCHEMBL1765041

SCHEMBL1765041

SCHEMBL1765041

O=C(OCc1c(F)cccc1Cl)c1csc(C2CCN(C(=O)Cn3nc(C(F)F)cc3C(F)F)CC2)n1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ PPARG P37231 1/20 0.44
▸ GAA P10253 1/20 0.40
▸ KMT2A Q03164 5/20 0.39
▸ MEN1 O00255 3/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ MAPT P10636 3/20 0.37
▸ TDP1 Q9NUW8 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ ALDH1A1 P00352 3/20 0.34
▸ ATM Q13315 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ FAAH O00519 1/20 0.34
▸ LMNA P02545 1/20 0.33
▸ HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1765535 0.95 PPARG (0.40) PPARGGAAKMT2AMEN1SMN1; SMN2
SCHEMBL15230716 0.91 GAA (0.38) PPARGGAAKMT2AMEN1SMN1; SMN2
SCHEMBL15230375 0.87 PPARG (0.35) PPARGGAAKMT2AMEN1SMN1; SMN2
SCHEMBL15231257 0.87 PPARG (0.38) PPARGGAAKMT2AMEN1SMN1; SMN2
SCHEMBL15230561 0.87 PPARG (0.37) PPARGGAAKMT2AMEN1SMN1; SMN2
SCHEMBL15231208 0.87 PPARG (0.37) PPARGGAAKMT2AMEN1SMN1; SMN2
SCHEMBL15230373 0.83 GAA (0.39) GAAKMT2AMEN1SMN1; SMN2MAPT
SCHEMBL1765111 0.83 PPARG (0.35) PPARGGAAKMT2AMAPTALDH1A1
SCHEMBL1119946 0.83 GAA (0.45) PPARGGAAKMT2AMEN1SMN1; SMN2
SCHEMBL1765165 0.83 CCR1 (0.44) PPARGGAAKMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015157005-A1 SUBSTITUTED TOLYL FUNGICIDE MIXTURES E I DU PONT DE NEMOURS AND COMPANY (US) 2015-10-15 — — WO claimed
US-20150266850-A1 SUBSTITUTED TOLYL FUNGICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2015-09-24 — — US claimed
WO-2014130409-A2 FUNGICIDAL PYRAZOLE MIXTURES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2014-08-28 — — WO claimed
US-12606548-B2 Fungicidal oxadiazoles FMC CORPORATION (US) 2026-04-21 — — US disclosed
US-12398107-B2 Fungicidal nitroanilino substituted pyrazoles FMC CORPORATION (US) 2025-08-26 — — US disclosed
US-20240324596-A1 SUBSTITUTED TOLYL FUNGICIDES FMC CORPORATION 2024-10-03 — — US disclosed
EP-4388876-A2 FUNGICIDAL NITROANILINO SUBSTITUTED PYRAZOLES FMC Corporation (US) 2024-06-26 — — EP disclosed
US-20240166638-A1 FUNGICIDAL OXADIAZOLES FMC CORP (US) 2024-05-23 — — US disclosed
EP-3847160-B1 FUNGICIDAL NITROANILINO SUBSTITUTED PYRAZOLES FMC CORP (US) 2024-05-08 — — EP disclosed
EP-3558984-B1 FUNGICIDAL OXADIAZOLES FMC CORP (US) 2023-08-02 — — EP disclosed
US-11708358-B2 Fungicidal oxadiazoles FMC CORPORATION (US) 2023-07-25 — — US disclosed
EP-2912020-A1 SUBSTITUTED TOLYL FUNGICIDES E. I. du Pont de Nemours and Company (US) 2015-09-02 — — EP disclosed
WO-2015123193-A1 FUNGICIDAL BENZODIPYRAZOLES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2015-08-20 — — WO disclosed
EP-2809157-A2 FUNGICIDAL PYRAZOLE MIXTURES E. I. Du Pont de Nemours and Company (US) 2014-12-10 — — EP disclosed
WO-2014172191-A1 FUNGICIDAL CARBOXAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2014-10-23 — — WO disclosed
WO-2014172190-A1 FUNGICIDAL AMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2014-10-23 — — WO disclosed
WO-2014130409-A2 FUNGICIDAL PYRAZOLE MIXTURES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2014-08-28 — — WO disclosed
WO-2014066120-A1 SUBSTITUTED TOLYL FUNGICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2014-05-01 — — WO disclosed
WO-2013116251-A2 FUNGICIDAL PYRAZOLE MIXTURES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-08-08 — — WO disclosed
US-20110124501-A1 Active compound combinations BAYER CROPSCIENCE AG (DE) 2011-05-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110124501-A1 Active compound combinations CYP51A1, CA4, BROX PPARG 402/4885GAA 90/4885KMT2A 3240/4885
US-20150266850-A1 SUBSTITUTED TOLYL FUNGICIDES TH, CYP1B1, CYP1A1 PPARG 4369/4885GAA 369/4885KMT2A 3392/4885
US-20240166638-A1 FUNGICIDAL OXADIAZOLES OXA1L, NOX1, TH PPARG 4551/4885GAA 516/4885KMT2A 4094/4885
US-20240324596-A1 SUBSTITUTED TOLYL FUNGICIDES TH, NAT1, CYP1B1 PPARG 4299/4885GAA 500/4885KMT2A 3653/4885
US-12398107-B2 Fungicidal nitroanilino substituted pyrazoles TH, NOX1, NOX3 PPARG 4264/4885GAA 1484/4885KMT2A 3322/4885
US-12606548-B2 Fungicidal oxadiazoles AOC2, AOC3, MT-CO3 PPARG 4789/4885GAA 2552/4885KMT2A 2992/4885
US-11708358-B2 Fungicidal oxadiazoles OXA1L, NOX1, TH PPARG 4551/4885GAA 516/4885KMT2A 4094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.