Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PDE8B | O95263 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3672913 | 0.80 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL11786372 | 0.75 | CASP1 (0.54) | NPC1RAB9ASMN1; SMN2HTTCASP1 | |
| SCHEMBL28030730 | 0.74 | CASP1 (0.46) | NPC1RAB9ASMN1; SMN2HTTCASP1 | |
| Cyanamide SCHEMBL8183499 | 0.70 | CASP1 (0.38) | NPC1RAB9ASMN1; SMN2CASP1CYP1A2 | |
| Water SCHEMBL6686404 | 0.69 | CASP1 (0.47) | NPC1RAB9ASMN1; SMN2CASP1CYP1A2 | |
| SCHEMBL1032160 | 0.69 | KDM4E (0.36) | NPC1RAB9ASMN1; SMN2HTTPOLB | |
| Water SCHEMBL845969 | 0.69 | CASP1 (0.47) | NPC1RAB9ASMN1; SMN2CASP1CYP1A2 | |
| Water SCHEMBL2230233 | 0.69 | CASP1 (0.47) | NPC1RAB9ASMN1; SMN2CASP1CYP1A2 | |
| SCHEMBL24108204 | 0.68 | TSHR (0.37) | NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL28892371 | 0.68 | NPC1 (0.32) | NPC1RAB9ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207448-B | Antimicrobial compounds, methods of making the same, and articles comprising the same | 医学科技研究公司 | 2020-12-29 | — | — | CN | disclosed |
| US-10189798-B2 | Antimicrobial compounds, methods of making the same and articles comprising them | MEDICAL TECHNOLOGY RESEARCH INC (US) | 2019-01-29 | — | — | US | disclosed |
| US-20180134672-A1 | ANTIMICROBIAL COMPOUNDS, METHODS OF MAKING THE SAME AND ARTICLES COMPRISING THEM | MEDICAL TECHNOLOGY RESEARCH INC | 2018-05-17 | — | — | US | disclosed |
| EP-3201182-A2 | ANTIMICROBIAL COMPOUNDS, METHODS OF MAKING THE SAME AND ARTICLES COMPRISING THEM | Medical Technology Research Inc. (US) | 2017-08-09 | — | — | EP | disclosed |
| WO-2016054284-A2 | ANTIMICROBIAL COMPOUNDS, METHODS OF MAKING THE SAME AND ARTICLES COMPRISING THEM | MEDICAL TECHNOLOGY RESEARCH INC (US) | 2016-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10189798-B2 | Antimicrobial compounds, methods of making the same and articles comprising them | GSDMD, TIAL1, AAAS | NPC1 1925/4885RAB9A 3868/4885SMN1; SMN2 3807/4885 |
| US-20180134672-A1 | ANTIMICROBIAL COMPOUNDS, METHODS OF MAKING THE SAME AND ARTICLES COMPRISING THEM | GSDMD, TIAL1, AAAS | NPC1 1925/4885RAB9A 3868/4885SMN1; SMN2 3807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.