Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.67 |
| ▸ | ABCG2 | Q9UNQ0 | 8/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.54 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.54 |
| ▸ | BCL9 | O00512 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL4628870 | 0.99 | ADORA3 (0.66) | ADORA3ABCG2ABCB1KDM4ECYP3A4 | |
| SCHEMBL5964713 | 0.87 | KDM4E (0.62) | ADORA3ABCG2ABCB1KDM4ECYP3A4 | |
| SCHEMBL380907 | 0.87 | ADORA3 (0.73) | ADORA3ABCG2ABCB1KDM4ECYP3A4 | |
| SCHEMBL774317 | 0.86 | ADORA3 (0.72) | ADORA3ABCG2ABCB1KDM4ECYP3A4 | |
| SCHEMBL19347141 | 0.84 | ABCG2 (0.72) | ABCG2ABCB1KDM4ECYP3A4MAPT | |
| SCHEMBL7554074 | 0.82 | PPARG (0.64) | ADORA3ABCG2ABCB1KDM4ECYP3A4 | |
| SCHEMBL5135081 | 0.82 | MGAM (0.51) | ADORA3ABCG2ABCB1KDM4ECYP3A4 | |
| SCHEMBL27798683 | 0.82 | ABCG2 (0.62) | ADORA3ABCG2ABCB1KDM4ECYP3A4 | |
| SCHEMBL28852933 | 0.81 | ABCG2 (0.64) | ADORA3ABCG2ABCB1KDM4ECYP3A4 | |
| SCHEMBL1664287 | 0.81 | ADORA3 (1.00) | ADORA3ABCG2ABCB1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561081-A | Application of CYP450 inhibitor in inhibiting or killing mites and treating xerophthalmia | 广州珍实视界生物医药科技有限公司 | 2024-02-13 | — | — | CN | claimed |
| EP-4258899-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONES AND THEIR USE | Firmenich SA (CH) | 2023-10-18 | — | — | EP | claimed |
| CN-116249520-A | Blocking replication of SARS-COV-2 and other pathogenic viruses using WNT/beta-catenin pathway inhibitors | 阿尔伯塔大学理事会 | 2023-06-09 | — | — | CN | claimed |
| CN-114867486-B | Composition containing black ginger extract and composition for oral administration | 丸善制药株式会社 | 2023-05-30 | — | — | CN | claimed |
| CN-115475157-A | Intestinal barrier improving agent | 株式会社资生堂 | 2022-12-16 | — | — | CN | claimed |
| WO-2022189155-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONES AND THEIR USE | FIRMENICH SA (CH) | 2022-09-15 | — | — | WO | claimed |
| CN-114867486-A | Composition containing Heijiang extract and oral composition | 丸善制药株式会社 | 2022-08-05 | — | — | CN | claimed |
| CN-109662984-B | Application of laggera pterodonta and rosemary extract in medicine for resisting type II dengue virus | 昆明医科大学 | 2022-07-26 | — | — | CN | claimed |
| WO-2021050449-A1 | COMPOSITIONS AND METHODS OF SUPPRESSING AVERSIVENESS OF PHARMACEUTICALS AND INGESTIBLE MATERIALS | MONELL CHEMICAL SENSES CENTER (US) | 2021-03-18 | — | — | WO | claimed |
| CN-107854507-B | Method for extracting flavonoid component from folium artemisiae argyi | 山东省中医药研究院 | 2021-01-22 | — | — | CN | claimed |
| EP-1660074-A1 | 7-CARBOXYMETHYLOXY-3 , 4 , 5-TRIMETHOXY FLAVONE MONOHYD RATE, THE PREPARATION METHOD AND USES THEREOF | Dong-A Pharmaceutical Co., Ltd. (KR) | 2006-05-31 | — | — | EP | claimed |
| WO-2006040621-A1 | OXY SUBSTITUTED FLAVONES AS ANTIHYPERGLYCEMIC AND ANTIDYSLIPIDEMIC AGENTS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-04-20 | — | — | WO | claimed |
| CN-1705473-A | Chromones and chromone derivatives and uses thereof | JENKEN BIOSCIENCES INC (US) | 2005-12-07 | — | — | CN | claimed |
| WO-2005023244-A1 | 7-CARBOXYMETHYLOXY-3', 4', 5-TRIMETHOXY FLAVONE MONOHYDRATE, THE PREPARATION METHOD AND USES THEREOF | DONG-A PHARMACEUTICAL CO., LTD. (KR) | 2005-03-17 | — | — | WO | claimed |
| EP-1351679-A2 | METHOD AND COMPOSITION FOR THE TREATMENT OF DIABETIC NEUROPATHY | The Quigley Corporation (US) | 2003-10-15 | — | — | EP | claimed |
| WO-2002049575-A2 | METHOD AND COMPOSITION FOR THE TREATMENT OF DIABETIC NEUROPATHY | THE QUIGLEY CORPORATION (US) | 2002-06-27 | — | — | WO | claimed |
| EP-0915864-A1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | Dong A Pharmaceutical Co. Ltd. (KR) | 1999-05-19 | — | — | EP | claimed |
| WO-1998004541-A1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | DONG A PHARMACEUTICAL CO., LTD. (KR) | 1998-02-05 | — | — | WO | claimed |
| CN-1033365-C | Composition based on hydrate lamellar lipides or liposomes, containing extract of scutellaria, or at least component thereof, and cosmeties or pharmaceutical, especially having anti-allergic,......... | LVMH RECH (FR) | 1996-11-27 | — | — | CN | claimed |
| CN-1037834-A | With hydration lamellar fat mutually or liposome is the compositions of main component, wherein contain the Radix Scutellariae extract or contain wherein a kind of component at least, and cosmetics or medicament, especially skin is had antiallergic, the compositions of antiinflammatory or defying age performance | LVMH RECH (FR) | 1989-12-13 | — | — | CN | claimed |